Inhibition of the CXCL9-CXCR3 axis suppresses the progression of experimental apical periodontitis by blocking macrophage migration and activation

Inhibition of the CXCL9-CXCR3 axis suppresses the progression of experimental apical periodontitis by blocking macrophage migration and activation

Abstract Apical periodontitis (AP) is an acute or chronic inflammatory disease caused by complex interactions between infected root canal and host immune system. It results in the induction of inflammatory mediators such as chemokines and cytokines leading to periapical tissue destruction. To unders...

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Autores principales: Tatsuya Hasegawa, V. Venkata Suresh, Yoshio Yahata, Masato Nakano, Shigeto Suzuki, Shigeki Suzuki, Satoru Yamada, Hideki Kitaura, Itaru Mizoguchi, Yuichiro Noiri, Keisuke Handa, Masahiro Saito
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/610192dc9c4643eab26692061c014b01
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