Complications of fluidotherapy in patients with acute pancreatitis: A contribution

Introduction: Aggressive fluid therapy is frequently suggested in the treatment of acute pancreatitis. However, there is some controversy about the effect of this therapy concerning the development of clinical complications and the need for surgery. Objectives: To explore the relationship between...

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Autores principales:	Carla Henriques, Jorge Pereira, Ana Cristina Matos, Catarina Afonso
Formato:	article
Lenguaje:	EN PT
Publicado:	Instituto Politécnico de Viseu 2018
Materias:	Acute pancreatitis Fluidotherapy Complications ROC curves Logistic regression Special aspects of education LC8-6691 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/610db3775bf846d7b902154c3187e811
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spelling	oai:doaj.org-article:610db3775bf846d7b902154c3187e8112021-12-02T11:47:41ZComplications of fluidotherapy in patients with acute pancreatitis: A contribution0873-30151647-662X10.29352/mill0206.02.00160https://doaj.org/article/610db3775bf846d7b902154c3187e8112018-05-01T00:00:00Zhttps://revistas.rcaap.pt/millenium/article/view/13464https://doaj.org/toc/0873-3015https://doaj.org/toc/1647-662XIntroduction: Aggressive fluid therapy is frequently suggested in the treatment of acute pancreatitis. However, there is some controversy about the effect of this therapy concerning the development of clinical complications and the need for surgery. Objectives: To explore the relationship between fluid administration in the first 48 hours and the development of local or systemic complications, to contribute to clarifying some open questions on this subject. Methods: This study is based on records of 109 patients admitted to the Surgical High Dependency Unit of Tondela Viseu Hospital Centre, between 2007 and 2012, with the diagnosis of acute pancreatitis. Data were explored, and statistical tests were used to identify variables that differentiate patients with complications. Receiver operating characteristic (ROC) curves allowed to relate the amount of fluids at 48 hours with the occurrence of each complication. Logistic regression models were used to identify independent risk factors for each complication. Results: There was no significant relationship between fluid therapy at 48 hours with death nor with the occurrence of systemic complications. As opposed, fluid therapy at 48 hours revealed to be associated with local and late complications, presence of infection and need for surgery. Conclusion: High levels of fluid therapy in the first 48 hours were associated with the development of complications.Carla HenriquesJorge PereiraJorge PereiraAna Cristina MatosAna Cristina MatosCatarina AfonsoCatarina AfonsoInstituto Politécnico de ViseuarticleAcute pancreatitisFluidotherapyComplicationsROC curvesLogistic regressionSpecial aspects of educationLC8-6691Public aspects of medicineRA1-1270ENPTMillenium, Iss 6, Pp 23-31 (2018)
institution	DOAJ
collection	DOAJ
language	EN PT
topic	Acute pancreatitis Fluidotherapy Complications ROC curves Logistic regression Special aspects of education LC8-6691 Public aspects of medicine RA1-1270
spellingShingle	Acute pancreatitis Fluidotherapy Complications ROC curves Logistic regression Special aspects of education LC8-6691 Public aspects of medicine RA1-1270 Carla Henriques Jorge Pereira Jorge Pereira Ana Cristina Matos Ana Cristina Matos Catarina Afonso Catarina Afonso Complications of fluidotherapy in patients with acute pancreatitis: A contribution
description	Introduction: Aggressive fluid therapy is frequently suggested in the treatment of acute pancreatitis. However, there is some controversy about the effect of this therapy concerning the development of clinical complications and the need for surgery. Objectives: To explore the relationship between fluid administration in the first 48 hours and the development of local or systemic complications, to contribute to clarifying some open questions on this subject. Methods: This study is based on records of 109 patients admitted to the Surgical High Dependency Unit of Tondela Viseu Hospital Centre, between 2007 and 2012, with the diagnosis of acute pancreatitis. Data were explored, and statistical tests were used to identify variables that differentiate patients with complications. Receiver operating characteristic (ROC) curves allowed to relate the amount of fluids at 48 hours with the occurrence of each complication. Logistic regression models were used to identify independent risk factors for each complication. Results: There was no significant relationship between fluid therapy at 48 hours with death nor with the occurrence of systemic complications. As opposed, fluid therapy at 48 hours revealed to be associated with local and late complications, presence of infection and need for surgery. Conclusion: High levels of fluid therapy in the first 48 hours were associated with the development of complications.
format	article
author	Carla Henriques Jorge Pereira Jorge Pereira Ana Cristina Matos Ana Cristina Matos Catarina Afonso Catarina Afonso
author_facet	Carla Henriques Jorge Pereira Jorge Pereira Ana Cristina Matos Ana Cristina Matos Catarina Afonso Catarina Afonso
author_sort	Carla Henriques
title	Complications of fluidotherapy in patients with acute pancreatitis: A contribution
title_short	Complications of fluidotherapy in patients with acute pancreatitis: A contribution
title_full	Complications of fluidotherapy in patients with acute pancreatitis: A contribution
title_fullStr	Complications of fluidotherapy in patients with acute pancreatitis: A contribution
title_full_unstemmed	Complications of fluidotherapy in patients with acute pancreatitis: A contribution
title_sort	complications of fluidotherapy in patients with acute pancreatitis: a contribution
publisher	Instituto Politécnico de Viseu
publishDate	2018
url	https://doaj.org/article/610db3775bf846d7b902154c3187e811
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Complications of fluidotherapy in patients with acute pancreatitis: A contribution

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