Is the Potable Water System an Advantageous Preinfection Niche for Bacteria Colonizing the Cystic Fibrosis Lung?

ABSTRACT People with cystic fibrosis are susceptible to lung infections from a variety of bacteria, a number of which also reside in the potable water system, including Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Achromobacter xylosoxidans, Burkholderia cepacia complex, and nontuberculosis...

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Autor principal: Matthew J. Wargo
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/611678e26c424afba048babd988d01cb
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spelling oai:doaj.org-article:611678e26c424afba048babd988d01cb2021-11-15T15:55:23ZIs the Potable Water System an Advantageous Preinfection Niche for Bacteria Colonizing the Cystic Fibrosis Lung?10.1128/mBio.00883-192150-7511https://doaj.org/article/611678e26c424afba048babd988d01cb2019-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00883-19https://doaj.org/toc/2150-7511ABSTRACT People with cystic fibrosis are susceptible to lung infections from a variety of bacteria, a number of which also reside in the potable water system, including Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Achromobacter xylosoxidans, Burkholderia cepacia complex, and nontuberculosis Mycobacteria. Here, I propose chemical and physical aspects of the potable water system along with bacterial lifestyle strategies in this system that may enhance successful colonization of cystic fibrosis lungs by these bacteria, including iron and copper levels, lipids, and low growth rates within low-oxygen biofilms.Matthew J. WargoAmerican Society for Microbiologyarticlebiofilmcystic fibrosisdrinking water microbiologyPseudomonasMicrobiologyQR1-502ENmBio, Vol 10, Iss 3 (2019)
institution DOAJ
collection DOAJ
language EN
topic biofilm
cystic fibrosis
drinking water microbiology
Pseudomonas
Microbiology
QR1-502
spellingShingle biofilm
cystic fibrosis
drinking water microbiology
Pseudomonas
Microbiology
QR1-502
Matthew J. Wargo
Is the Potable Water System an Advantageous Preinfection Niche for Bacteria Colonizing the Cystic Fibrosis Lung?
description ABSTRACT People with cystic fibrosis are susceptible to lung infections from a variety of bacteria, a number of which also reside in the potable water system, including Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Achromobacter xylosoxidans, Burkholderia cepacia complex, and nontuberculosis Mycobacteria. Here, I propose chemical and physical aspects of the potable water system along with bacterial lifestyle strategies in this system that may enhance successful colonization of cystic fibrosis lungs by these bacteria, including iron and copper levels, lipids, and low growth rates within low-oxygen biofilms.
format article
author Matthew J. Wargo
author_facet Matthew J. Wargo
author_sort Matthew J. Wargo
title Is the Potable Water System an Advantageous Preinfection Niche for Bacteria Colonizing the Cystic Fibrosis Lung?
title_short Is the Potable Water System an Advantageous Preinfection Niche for Bacteria Colonizing the Cystic Fibrosis Lung?
title_full Is the Potable Water System an Advantageous Preinfection Niche for Bacteria Colonizing the Cystic Fibrosis Lung?
title_fullStr Is the Potable Water System an Advantageous Preinfection Niche for Bacteria Colonizing the Cystic Fibrosis Lung?
title_full_unstemmed Is the Potable Water System an Advantageous Preinfection Niche for Bacteria Colonizing the Cystic Fibrosis Lung?
title_sort is the potable water system an advantageous preinfection niche for bacteria colonizing the cystic fibrosis lung?
publisher American Society for Microbiology
publishDate 2019
url https://doaj.org/article/611678e26c424afba048babd988d01cb
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