BCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcoma.
The EWS/FLI translocation product is the causative oncogene in Ewing sarcoma and acts as an aberrant transcription factor. EWS/FLI dysregulates gene expression during tumorigenesis by abnormally activating or repressing genes. The expression levels of thousands of genes are affected in Ewing sarcoma...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2013
|
| Subjects: | |
| Online Access: | https://doaj.org/article/6116bd5bc3a94646a34c47a8b40bb2a9 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|