Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly

As assembling 60S subunits transit from the nucleolus to the nucleoplasm, they undergo significant changes in protein composition and structure. Here, the authors provide a structural view of interconnected events during the middle steps of assembly that include the maturation of the central protube...

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Autores principales:	Jelena Micic, Yu Li, Shan Wu, Daniel Wilson, Beril Tutuncuoglu, Ning Gao, John L. Woolford
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/611c8aa58da84f4380a6473f6b8702a1
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spelling	oai:doaj.org-article:611c8aa58da84f4380a6473f6b8702a12021-12-02T18:47:02ZCoupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly10.1038/s41467-020-17534-52041-1723https://doaj.org/article/611c8aa58da84f4380a6473f6b8702a12020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17534-5https://doaj.org/toc/2041-1723As assembling 60S subunits transit from the nucleolus to the nucleoplasm, they undergo significant changes in protein composition and structure. Here, the authors provide a structural view of interconnected events during the middle steps of assembly that include the maturation of the central protuberance, the peptidyltransferase center and the nascent polypeptide exit tunnel.Jelena MicicYu LiShan WuDaniel WilsonBeril TutuncuogluNing GaoJohn L. WoolfordNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jelena Micic Yu Li Shan Wu Daniel Wilson Beril Tutuncuoglu Ning Gao John L. Woolford Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly
description	As assembling 60S subunits transit from the nucleolus to the nucleoplasm, they undergo significant changes in protein composition and structure. Here, the authors provide a structural view of interconnected events during the middle steps of assembly that include the maturation of the central protuberance, the peptidyltransferase center and the nascent polypeptide exit tunnel.
format	article
author	Jelena Micic Yu Li Shan Wu Daniel Wilson Beril Tutuncuoglu Ning Gao John L. Woolford
author_facet	Jelena Micic Yu Li Shan Wu Daniel Wilson Beril Tutuncuoglu Ning Gao John L. Woolford
author_sort	Jelena Micic
title	Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly
title_short	Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly
title_full	Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly
title_fullStr	Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly
title_full_unstemmed	Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly
title_sort	coupling of 5s rnp rotation with maturation of functional centers during large ribosomal subunit assembly
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/611c8aa58da84f4380a6473f6b8702a1
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Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly

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