Induction of premalignant host responses by cathepsin x/z-deficiency in Helicobacter pylori-infected mice.
Helicobacter pylori are responsible for the induction of chronic gastric inflammation progressing to atrophy, metaplasia, and gastric cancer. The overexpression of Cathepsin X/Z (Ctsz) in H. pylori-infected mucosa and gastric cancer is mediated predominantly by an augmented migration of ctsz(-/-)pos...
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Auteurs principaux: | Sabine Krueger, Anja Bernhardt, Thomas Kalinski, Martin Baldensperger, Michael Zeh, Anne Teller, Daniela Adolf, Thomas Reinheckel, Albert Roessner, Doerthe Kuester |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/612aaf29cdcb401cb9bdc5d0d3f564a3 |
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