Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer

Defects in non-canonical Wnt/planar cell polarity signalling have recently been linked to breast cancer aggressiveness. Puvirajesinghe et al. identify VANGL2, p62/SQSTM1 and JNK as important players in this pathway which may be amenable to therapeutic intervention in breast cancer.

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Autores principales:	Tania M. Puvirajesinghe, François Bertucci, Ashish Jain, Pierluigi Scerbo, Edwige Belotti, Stéphane Audebert, Michael Sebbagh, Marc Lopez, Andreas Brech, Pascal Finetti, Emmanuelle Charafe-Jauffret, Max Chaffanet, Rémy Castellano, Audrey Restouin, Sylvie Marchetto, Yves Collette, Anthony Gonçalvès, Ian Macara, Daniel Birnbaum, Laurent Kodjabachian, Terje Johansen, Jean-Paul Borg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/613bb808db014e17b9b94d6f70ddaa1f
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spelling	oai:doaj.org-article:613bb808db014e17b9b94d6f70ddaa1f2021-12-02T15:35:45ZIdentification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer10.1038/ncomms103182041-1723https://doaj.org/article/613bb808db014e17b9b94d6f70ddaa1f2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10318https://doaj.org/toc/2041-1723Defects in non-canonical Wnt/planar cell polarity signalling have recently been linked to breast cancer aggressiveness. Puvirajesinghe et al. identify VANGL2, p62/SQSTM1 and JNK as important players in this pathway which may be amenable to therapeutic intervention in breast cancer.Tania M. PuvirajesingheFrançois BertucciAshish JainPierluigi ScerboEdwige BelottiStéphane AudebertMichael SebbaghMarc LopezAndreas BrechPascal FinettiEmmanuelle Charafe-JauffretMax ChaffanetRémy CastellanoAudrey RestouinSylvie MarchettoYves ColletteAnthony GonçalvèsIan MacaraDaniel BirnbaumLaurent KodjabachianTerje JohansenJean-Paul BorgNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tania M. Puvirajesinghe François Bertucci Ashish Jain Pierluigi Scerbo Edwige Belotti Stéphane Audebert Michael Sebbagh Marc Lopez Andreas Brech Pascal Finetti Emmanuelle Charafe-Jauffret Max Chaffanet Rémy Castellano Audrey Restouin Sylvie Marchetto Yves Collette Anthony Gonçalvès Ian Macara Daniel Birnbaum Laurent Kodjabachian Terje Johansen Jean-Paul Borg Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer
description	Defects in non-canonical Wnt/planar cell polarity signalling have recently been linked to breast cancer aggressiveness. Puvirajesinghe et al. identify VANGL2, p62/SQSTM1 and JNK as important players in this pathway which may be amenable to therapeutic intervention in breast cancer.
format	article
author	Tania M. Puvirajesinghe François Bertucci Ashish Jain Pierluigi Scerbo Edwige Belotti Stéphane Audebert Michael Sebbagh Marc Lopez Andreas Brech Pascal Finetti Emmanuelle Charafe-Jauffret Max Chaffanet Rémy Castellano Audrey Restouin Sylvie Marchetto Yves Collette Anthony Gonçalvès Ian Macara Daniel Birnbaum Laurent Kodjabachian Terje Johansen Jean-Paul Borg
author_facet	Tania M. Puvirajesinghe François Bertucci Ashish Jain Pierluigi Scerbo Edwige Belotti Stéphane Audebert Michael Sebbagh Marc Lopez Andreas Brech Pascal Finetti Emmanuelle Charafe-Jauffret Max Chaffanet Rémy Castellano Audrey Restouin Sylvie Marchetto Yves Collette Anthony Gonçalvès Ian Macara Daniel Birnbaum Laurent Kodjabachian Terje Johansen Jean-Paul Borg
author_sort	Tania M. Puvirajesinghe
title	Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer
title_short	Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer
title_full	Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer
title_fullStr	Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer
title_full_unstemmed	Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer
title_sort	identification of p62/sqstm1 as a component of non-canonical wnt vangl2–jnk signalling in breast cancer
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/613bb808db014e17b9b94d6f70ddaa1f
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Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer

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