Unique association between global DNA hypomethylation and chromosomal alterations in human hepatocellular carcinoma.

Unique association between global DNA hypomethylation and chromosomal alterations in human hepatocellular carcinoma.

Global DNA hypomethylation is a characteristic feature of cancer cells that closely associates with chromosomal instability (CIN). However, the association between these characteristics during hepatocarcinogenesis remains unclear. Herein, we determined the relationship between hypomethylation and CI...

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Autores principales: Naoshi Nishida, Masatoshi Kudo, Takafumi Nishimura, Tadaaki Arizumi, Masahiro Takita, Satoshi Kitai, Norihisa Yada, Satoru Hagiwara, Tatsuo Inoue, Yasunori Minami, Kazuomi Ueshima, Toshiharu Sakurai, Naosuke Yokomichi, Takeshi Nagasaka, Ajay Goel
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/6147168e24e147ae821b2defde2d8d5e
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