Repo-Man/PP1 regulates heterochromatin formation in interphase

Repo-Man is a chromosome-binding subunit of protein phosphatase 1 to regulate mitosis. Here, de Castro and colleagues show that Repo-Man also regulates heterochromatin during interphase, and regulates gene repression and chromatin organization.

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Autores principales: Inês J. de Castro, James Budzak, Maria L. Di Giacinto, Lorena Ligammari, Ezgi Gokhan, Christos Spanos, Daniela Moralli, Christine Richardson, Jose I. de las Heras, Silvia Salatino, Eric C. Schirmer, Katharine S. Ullman, Wendy A. Bickmore, Catherine Green, Juri Rappsilber, Sarah Lamble, Martin W. Goldberg, Veronica Vinciotti, Paola Vagnarelli
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/614dab2625cb407a8fec9084fc97d570
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spelling oai:doaj.org-article:614dab2625cb407a8fec9084fc97d5702021-12-02T17:06:25ZRepo-Man/PP1 regulates heterochromatin formation in interphase10.1038/ncomms140482041-1723https://doaj.org/article/614dab2625cb407a8fec9084fc97d5702017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14048https://doaj.org/toc/2041-1723Repo-Man is a chromosome-binding subunit of protein phosphatase 1 to regulate mitosis. Here, de Castro and colleagues show that Repo-Man also regulates heterochromatin during interphase, and regulates gene repression and chromatin organization.Inês J. de CastroJames BudzakMaria L. Di GiacintoLorena LigammariEzgi GokhanChristos SpanosDaniela MoralliChristine RichardsonJose I. de las HerasSilvia SalatinoEric C. SchirmerKatharine S. UllmanWendy A. BickmoreCatherine GreenJuri RappsilberSarah LambleMartin W. GoldbergVeronica VinciottiPaola VagnarelliNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Inês J. de Castro
James Budzak
Maria L. Di Giacinto
Lorena Ligammari
Ezgi Gokhan
Christos Spanos
Daniela Moralli
Christine Richardson
Jose I. de las Heras
Silvia Salatino
Eric C. Schirmer
Katharine S. Ullman
Wendy A. Bickmore
Catherine Green
Juri Rappsilber
Sarah Lamble
Martin W. Goldberg
Veronica Vinciotti
Paola Vagnarelli
Repo-Man/PP1 regulates heterochromatin formation in interphase
description Repo-Man is a chromosome-binding subunit of protein phosphatase 1 to regulate mitosis. Here, de Castro and colleagues show that Repo-Man also regulates heterochromatin during interphase, and regulates gene repression and chromatin organization.
format article
author Inês J. de Castro
James Budzak
Maria L. Di Giacinto
Lorena Ligammari
Ezgi Gokhan
Christos Spanos
Daniela Moralli
Christine Richardson
Jose I. de las Heras
Silvia Salatino
Eric C. Schirmer
Katharine S. Ullman
Wendy A. Bickmore
Catherine Green
Juri Rappsilber
Sarah Lamble
Martin W. Goldberg
Veronica Vinciotti
Paola Vagnarelli
author_facet Inês J. de Castro
James Budzak
Maria L. Di Giacinto
Lorena Ligammari
Ezgi Gokhan
Christos Spanos
Daniela Moralli
Christine Richardson
Jose I. de las Heras
Silvia Salatino
Eric C. Schirmer
Katharine S. Ullman
Wendy A. Bickmore
Catherine Green
Juri Rappsilber
Sarah Lamble
Martin W. Goldberg
Veronica Vinciotti
Paola Vagnarelli
author_sort Inês J. de Castro
title Repo-Man/PP1 regulates heterochromatin formation in interphase
title_short Repo-Man/PP1 regulates heterochromatin formation in interphase
title_full Repo-Man/PP1 regulates heterochromatin formation in interphase
title_fullStr Repo-Man/PP1 regulates heterochromatin formation in interphase
title_full_unstemmed Repo-Man/PP1 regulates heterochromatin formation in interphase
title_sort repo-man/pp1 regulates heterochromatin formation in interphase
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/614dab2625cb407a8fec9084fc97d570
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