Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors

Retinal waves are important for visual system development. However, the mechanism involved in their generation remains largely unknown. Here using in vivotwo-photon imaging the authors identify the presence of retinal waves in zebrafish larvae and find that they are initiated at bipolar cells via pr...

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Bibliographic Details
Main Authors: Rong-wei Zhang, Xiao-quan Li, Koichi Kawakami, Jiu-lin Du
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/614ff8f7d7484ec99b8fa5a89efc0b76
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Summary:Retinal waves are important for visual system development. However, the mechanism involved in their generation remains largely unknown. Here using in vivotwo-photon imaging the authors identify the presence of retinal waves in zebrafish larvae and find that they are initiated at bipolar cells via presynaptic NMDARs.