Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors

Retinal waves are important for visual system development. However, the mechanism involved in their generation remains largely unknown. Here using in vivotwo-photon imaging the authors identify the presence of retinal waves in zebrafish larvae and find that they are initiated at bipolar cells via pr...

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Autores principales: Rong-wei Zhang, Xiao-quan Li, Koichi Kawakami, Jiu-lin Du
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/614ff8f7d7484ec99b8fa5a89efc0b76
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spelling oai:doaj.org-article:614ff8f7d7484ec99b8fa5a89efc0b762021-12-02T15:34:57ZStereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors10.1038/ncomms126502041-1723https://doaj.org/article/614ff8f7d7484ec99b8fa5a89efc0b762016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12650https://doaj.org/toc/2041-1723Retinal waves are important for visual system development. However, the mechanism involved in their generation remains largely unknown. Here using in vivotwo-photon imaging the authors identify the presence of retinal waves in zebrafish larvae and find that they are initiated at bipolar cells via presynaptic NMDARs.Rong-wei ZhangXiao-quan LiKoichi KawakamiJiu-lin DuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Rong-wei Zhang
Xiao-quan Li
Koichi Kawakami
Jiu-lin Du
Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
description Retinal waves are important for visual system development. However, the mechanism involved in their generation remains largely unknown. Here using in vivotwo-photon imaging the authors identify the presence of retinal waves in zebrafish larvae and find that they are initiated at bipolar cells via presynaptic NMDARs.
format article
author Rong-wei Zhang
Xiao-quan Li
Koichi Kawakami
Jiu-lin Du
author_facet Rong-wei Zhang
Xiao-quan Li
Koichi Kawakami
Jiu-lin Du
author_sort Rong-wei Zhang
title Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
title_short Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
title_full Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
title_fullStr Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
title_full_unstemmed Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
title_sort stereotyped initiation of retinal waves by bipolar cells via presynaptic nmda autoreceptors
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/614ff8f7d7484ec99b8fa5a89efc0b76
work_keys_str_mv AT rongweizhang stereotypedinitiationofretinalwavesbybipolarcellsviapresynapticnmdaautoreceptors
AT xiaoquanli stereotypedinitiationofretinalwavesbybipolarcellsviapresynapticnmdaautoreceptors
AT koichikawakami stereotypedinitiationofretinalwavesbybipolarcellsviapresynapticnmdaautoreceptors
AT jiulindu stereotypedinitiationofretinalwavesbybipolarcellsviapresynapticnmdaautoreceptors
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