Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors

Retinal waves are important for visual system development. However, the mechanism involved in their generation remains largely unknown. Here using in vivotwo-photon imaging the authors identify the presence of retinal waves in zebrafish larvae and find that they are initiated at bipolar cells via pr...

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Main Authors:	Rong-wei Zhang, Xiao-quan Li, Koichi Kawakami, Jiu-lin Du
Format:	article
Language:	EN
Published:	Nature Portfolio 2016
Subjects:	Science Q
Online Access:	https://doaj.org/article/614ff8f7d7484ec99b8fa5a89efc0b76
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spelling	oai:doaj.org-article:614ff8f7d7484ec99b8fa5a89efc0b762021-12-02T15:34:57ZStereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors10.1038/ncomms126502041-1723https://doaj.org/article/614ff8f7d7484ec99b8fa5a89efc0b762016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12650https://doaj.org/toc/2041-1723Retinal waves are important for visual system development. However, the mechanism involved in their generation remains largely unknown. Here using in vivotwo-photon imaging the authors identify the presence of retinal waves in zebrafish larvae and find that they are initiated at bipolar cells via presynaptic NMDARs.Rong-wei ZhangXiao-quan LiKoichi KawakamiJiu-lin DuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rong-wei Zhang Xiao-quan Li Koichi Kawakami Jiu-lin Du Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
description	Retinal waves are important for visual system development. However, the mechanism involved in their generation remains largely unknown. Here using in vivotwo-photon imaging the authors identify the presence of retinal waves in zebrafish larvae and find that they are initiated at bipolar cells via presynaptic NMDARs.
format	article
author	Rong-wei Zhang Xiao-quan Li Koichi Kawakami Jiu-lin Du
author_facet	Rong-wei Zhang Xiao-quan Li Koichi Kawakami Jiu-lin Du
author_sort	Rong-wei Zhang
title	Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
title_short	Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
title_full	Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
title_fullStr	Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
title_full_unstemmed	Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
title_sort	stereotyped initiation of retinal waves by bipolar cells via presynaptic nmda autoreceptors
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/614ff8f7d7484ec99b8fa5a89efc0b76
work_keys_str_mv	AT rongweizhang stereotypedinitiationofretinalwavesbybipolarcellsviapresynapticnmdaautoreceptors AT xiaoquanli stereotypedinitiationofretinalwavesbybipolarcellsviapresynapticnmdaautoreceptors AT koichikawakami stereotypedinitiationofretinalwavesbybipolarcellsviapresynapticnmdaautoreceptors AT jiulindu stereotypedinitiationofretinalwavesbybipolarcellsviapresynapticnmdaautoreceptors
_version_	1718386721768341504

Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors

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