PSMs of hypervirulent Staphylococcus aureus act as intracellular toxins that kill infected osteoblasts.

PSMs of hypervirulent Staphylococcus aureus act as intracellular toxins that kill infected osteoblasts.

Epidemic community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is associated with more severe and acute forms of osteomyelitis than healthcare-associated (HA-) MRSA. Although S. aureus is now recognized as a facultative intracellular pathogen, the contribution of osteoblast invasi...

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Bibliographic Details
Main Authors: Jean-Philippe Rasigade, Sophie Trouillet-Assant, Tristan Ferry, Binh An Diep, Anaïs Sapin, Yannick Lhoste, Jérémy Ranfaing, Cédric Badiou, Yvonne Benito, Michèle Bes, Florence Couzon, Sylvestre Tigaud, Gérard Lina, Jérôme Etienne, François Vandenesch, Frédéric Laurent
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/615951f176744a948d2105ac0c9b8534
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