Association of Follicular Response with Outcome of Intrauterine Insemination in Infertile Women

BACKGROUND AND OBJECTIVE: Intrauterine insemination (IUI) after ovulation induction is one of the infertility treatment methods that used before more invasive assisted reproductive techniques (ART) due to simplicity and low expenses. This procedure is performed in different kinds of subfertility suc...

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Autores principales: Z Basirat, M Shamsoddin
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Lenguaje:EN
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Publicado: Babol University of Medical Sciences 2009
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spelling oai:doaj.org-article:6163a58d493a4b35b3d606e1944137bd2021-11-10T09:02:34ZAssociation of Follicular Response with Outcome of Intrauterine Insemination in Infertile Women1561-41072251-7170https://doaj.org/article/6163a58d493a4b35b3d606e1944137bd2009-04-01T00:00:00Zhttp://jbums.org/article-1-3147-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Intrauterine insemination (IUI) after ovulation induction is one of the infertility treatment methods that used before more invasive assisted reproductive techniques (ART) due to simplicity and low expenses. This procedure is performed in different kinds of subfertility such as male factors, cervical factors and unexplained infertility. The aim of this study was to determine the association of follicular response with IUI outcome.METHODS: This case-control study was done on 267 infertile couples under 35 years old in Fatemeh Zahra infertility center affiliated to Babol University of medical sciences, Babol, Iran that the result of IUI was positive in 89 cases and it was negative in 178 cases. Women with cervical factor and ovulation dysfunction who underwent clomiphene citrate, or clomiphene citrate and human menopausal gonadotropin were included in this study. Data include: age, duration of infertility, follicle number, number of IUI cycles and outcome were analyzed. FINDINGS: Pregnancy occurred in 89(33.3%) of 267 cases. The number of follicle in pregnant women (2.8±1.4) was significantly higher than non-pregnant women (1.9±0.9) (p=0.000). The mean age of pregnant women (24.3±3.8 years) was significantly lower than non-pregnant women (26.4±4.8 years) (p=0.000). The duration of infertility in pregnant women (2.67±2.3 years) was significantly lower than non-pregnant women (4.5±3.1 years) (p=0.000). There was not significant correlation between number of follicle with women age (p=0.599, r=0.032) and duration of infertility (p=0.475, r=-0.044)CONCLUSION: According to the results of this study, success of IUI in ovarian stimulation cycles depended on the number of follicle. So it is recommended to consider the number of follicle for success of IUI in ovarian stimulation cycles.Z Basirat,M ShamsoddinBabol University of Medical Sciencesarticleintrauterine inseminationfollicle numberinfertilityfollicular responsepregnancyMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 11, Iss 1, Pp 19-24 (2009)
institution DOAJ
collection DOAJ
language EN
FA
topic intrauterine insemination
follicle number
infertility
follicular response
pregnancy
Medicine
R
Medicine (General)
R5-920
spellingShingle intrauterine insemination
follicle number
infertility
follicular response
pregnancy
Medicine
R
Medicine (General)
R5-920
Z Basirat,
M Shamsoddin
Association of Follicular Response with Outcome of Intrauterine Insemination in Infertile Women
description BACKGROUND AND OBJECTIVE: Intrauterine insemination (IUI) after ovulation induction is one of the infertility treatment methods that used before more invasive assisted reproductive techniques (ART) due to simplicity and low expenses. This procedure is performed in different kinds of subfertility such as male factors, cervical factors and unexplained infertility. The aim of this study was to determine the association of follicular response with IUI outcome.METHODS: This case-control study was done on 267 infertile couples under 35 years old in Fatemeh Zahra infertility center affiliated to Babol University of medical sciences, Babol, Iran that the result of IUI was positive in 89 cases and it was negative in 178 cases. Women with cervical factor and ovulation dysfunction who underwent clomiphene citrate, or clomiphene citrate and human menopausal gonadotropin were included in this study. Data include: age, duration of infertility, follicle number, number of IUI cycles and outcome were analyzed. FINDINGS: Pregnancy occurred in 89(33.3%) of 267 cases. The number of follicle in pregnant women (2.8±1.4) was significantly higher than non-pregnant women (1.9±0.9) (p=0.000). The mean age of pregnant women (24.3±3.8 years) was significantly lower than non-pregnant women (26.4±4.8 years) (p=0.000). The duration of infertility in pregnant women (2.67±2.3 years) was significantly lower than non-pregnant women (4.5±3.1 years) (p=0.000). There was not significant correlation between number of follicle with women age (p=0.599, r=0.032) and duration of infertility (p=0.475, r=-0.044)CONCLUSION: According to the results of this study, success of IUI in ovarian stimulation cycles depended on the number of follicle. So it is recommended to consider the number of follicle for success of IUI in ovarian stimulation cycles.
format article
author Z Basirat,
M Shamsoddin
author_facet Z Basirat,
M Shamsoddin
author_sort Z Basirat,
title Association of Follicular Response with Outcome of Intrauterine Insemination in Infertile Women
title_short Association of Follicular Response with Outcome of Intrauterine Insemination in Infertile Women
title_full Association of Follicular Response with Outcome of Intrauterine Insemination in Infertile Women
title_fullStr Association of Follicular Response with Outcome of Intrauterine Insemination in Infertile Women
title_full_unstemmed Association of Follicular Response with Outcome of Intrauterine Insemination in Infertile Women
title_sort association of follicular response with outcome of intrauterine insemination in infertile women
publisher Babol University of Medical Sciences
publishDate 2009
url https://doaj.org/article/6163a58d493a4b35b3d606e1944137bd
work_keys_str_mv AT zbasirat associationoffollicularresponsewithoutcomeofintrauterineinseminationininfertilewomen
AT mshamsoddin associationoffollicularresponsewithoutcomeofintrauterineinseminationininfertilewomen
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