Reconstructing aspects of human embryogenesis with pluripotent stem cells

Human early development remains largely inaccessible, owing to technical and ethical limitations of working with natural embryos. Here the authors assess the extent to which human expanded pluripotent stem cells can specify distinct cell lineages and capture aspects of early human embryogenesis.

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Autores principales:	Berna Sozen, Victoria Jorgensen, Bailey A. T. Weatherbee, Sisi Chen, Meng Zhu, Magdalena Zernicka-Goetz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/61641a4f11414d829e6fb891fdcf2245
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spelling	oai:doaj.org-article:61641a4f11414d829e6fb891fdcf22452021-12-02T17:27:04ZReconstructing aspects of human embryogenesis with pluripotent stem cells10.1038/s41467-021-25853-42041-1723https://doaj.org/article/61641a4f11414d829e6fb891fdcf22452021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25853-4https://doaj.org/toc/2041-1723Human early development remains largely inaccessible, owing to technical and ethical limitations of working with natural embryos. Here the authors assess the extent to which human expanded pluripotent stem cells can specify distinct cell lineages and capture aspects of early human embryogenesis.Berna SozenVictoria JorgensenBailey A. T. WeatherbeeSisi ChenMeng ZhuMagdalena Zernicka-GoetzNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Berna Sozen Victoria Jorgensen Bailey A. T. Weatherbee Sisi Chen Meng Zhu Magdalena Zernicka-Goetz Reconstructing aspects of human embryogenesis with pluripotent stem cells
description	Human early development remains largely inaccessible, owing to technical and ethical limitations of working with natural embryos. Here the authors assess the extent to which human expanded pluripotent stem cells can specify distinct cell lineages and capture aspects of early human embryogenesis.
format	article
author	Berna Sozen Victoria Jorgensen Bailey A. T. Weatherbee Sisi Chen Meng Zhu Magdalena Zernicka-Goetz
author_facet	Berna Sozen Victoria Jorgensen Bailey A. T. Weatherbee Sisi Chen Meng Zhu Magdalena Zernicka-Goetz
author_sort	Berna Sozen
title	Reconstructing aspects of human embryogenesis with pluripotent stem cells
title_short	Reconstructing aspects of human embryogenesis with pluripotent stem cells
title_full	Reconstructing aspects of human embryogenesis with pluripotent stem cells
title_fullStr	Reconstructing aspects of human embryogenesis with pluripotent stem cells
title_full_unstemmed	Reconstructing aspects of human embryogenesis with pluripotent stem cells
title_sort	reconstructing aspects of human embryogenesis with pluripotent stem cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/61641a4f11414d829e6fb891fdcf2245
work_keys_str_mv	AT bernasozen reconstructingaspectsofhumanembryogenesiswithpluripotentstemcells AT victoriajorgensen reconstructingaspectsofhumanembryogenesiswithpluripotentstemcells AT baileyatweatherbee reconstructingaspectsofhumanembryogenesiswithpluripotentstemcells AT sisichen reconstructingaspectsofhumanembryogenesiswithpluripotentstemcells AT mengzhu reconstructingaspectsofhumanembryogenesiswithpluripotentstemcells AT magdalenazernickagoetz reconstructingaspectsofhumanembryogenesiswithpluripotentstemcells
_version_	1718380792022827008

Reconstructing aspects of human embryogenesis with pluripotent stem cells

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