High Fat Diet Triggers a Reduction in Body Fat Mass in Female Mice Deficient for Utx demethylase

High Fat Diet Triggers a Reduction in Body Fat Mass in Female Mice Deficient for Utx demethylase

Abstract Obesity increases the risk of metabolic disorders like diabetes mellitus and dyslipidemia. However, how metabolic status is sensed and regulates cellular behavior is unclear. Utx is an H3K27 demethylase that influences adipocyte function in vitro. To examine its role in vivo, we generated m...

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Autores principales: Kazushige Ota, Akiyoshi Komuro, Hisayuki Amano, Akinori Kanai, Kai Ge, Takeshi Ueda, Hitoshi Okada
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/61739a8843d14250a281079be978bd08
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