A biomaterial with a channel-like pore architecture induces endochondral healing of bone defects

A bioengineering approach to enhance the regeneration of large bone defects is lacking. Here, the authors show that a biomaterial scaffold with a channel-like pore architecture enables organized endochondral ossification through directional cell recruitment and extracellular matrix alignment.

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Auteurs principaux: A. Petersen, A. Princ, G. Korus, A. Ellinghaus, H. Leemhuis, A. Herrera, A. Klaumünzer, S. Schreivogel, A. Woloszyk, K. Schmidt-Bleek, S. Geissler, I. Heschel, G. N. Duda
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/6173f1f6a0e44b58b39f4c51d976aca8
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