Bacterial cyclic diguanylate signaling networks sense temperature

Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility, biofilm production and virulence. Here, the authors identify a thermosensitive enzyme that synthesizes c-di-GMP and modulates temperature-dependent motility, biofilm development and virulence in the opportunist...

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Autores principales: Henrik Almblad, Trevor E. Randall, Fanny Liu, Katherine Leblanc, Ryan A. Groves, Weerayuth Kittichotirat, Geoffrey L. Winsor, Nicolas Fournier, Emily Au, Julie Groizeleau, Jacquelyn D. Rich, Yuefei Lou, Elise Granton, Laura K. Jennings, Larissa A. Singletary, Tara M. L. Winstone, Nathan M. Good, Roger E. Bumgarner, Michael F. Hynes, Manu Singh, Maria Silvina Stietz, Fiona S. L. Brinkman, Ayush Kumar, Ann Karen Cornelia Brassinga, Matthew R. Parsek, Boo Shan Tseng, Ian A. Lewis, Bryan G. Yipp, Justin L. MacCallum, Joe Jonathan Harrison
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6182b1bdedda46118764d49013acab00
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spelling oai:doaj.org-article:6182b1bdedda46118764d49013acab002021-12-02T14:23:03ZBacterial cyclic diguanylate signaling networks sense temperature10.1038/s41467-021-22176-22041-1723https://doaj.org/article/6182b1bdedda46118764d49013acab002021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22176-2https://doaj.org/toc/2041-1723Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility, biofilm production and virulence. Here, the authors identify a thermosensitive enzyme that synthesizes c-di-GMP and modulates temperature-dependent motility, biofilm development and virulence in the opportunistic pathogen Pseudomonas aeruginosa.Henrik AlmbladTrevor E. RandallFanny LiuKatherine LeblancRyan A. GrovesWeerayuth KittichotiratGeoffrey L. WinsorNicolas FournierEmily AuJulie GroizeleauJacquelyn D. RichYuefei LouElise GrantonLaura K. JenningsLarissa A. SingletaryTara M. L. WinstoneNathan M. GoodRoger E. BumgarnerMichael F. HynesManu SinghMaria Silvina StietzFiona S. L. BrinkmanAyush KumarAnn Karen Cornelia BrassingaMatthew R. ParsekBoo Shan TsengIan A. LewisBryan G. YippJustin L. MacCallumJoe Jonathan HarrisonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Henrik Almblad
Trevor E. Randall
Fanny Liu
Katherine Leblanc
Ryan A. Groves
Weerayuth Kittichotirat
Geoffrey L. Winsor
Nicolas Fournier
Emily Au
Julie Groizeleau
Jacquelyn D. Rich
Yuefei Lou
Elise Granton
Laura K. Jennings
Larissa A. Singletary
Tara M. L. Winstone
Nathan M. Good
Roger E. Bumgarner
Michael F. Hynes
Manu Singh
Maria Silvina Stietz
Fiona S. L. Brinkman
Ayush Kumar
Ann Karen Cornelia Brassinga
Matthew R. Parsek
Boo Shan Tseng
Ian A. Lewis
Bryan G. Yipp
Justin L. MacCallum
Joe Jonathan Harrison
Bacterial cyclic diguanylate signaling networks sense temperature
description Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility, biofilm production and virulence. Here, the authors identify a thermosensitive enzyme that synthesizes c-di-GMP and modulates temperature-dependent motility, biofilm development and virulence in the opportunistic pathogen Pseudomonas aeruginosa.
format article
author Henrik Almblad
Trevor E. Randall
Fanny Liu
Katherine Leblanc
Ryan A. Groves
Weerayuth Kittichotirat
Geoffrey L. Winsor
Nicolas Fournier
Emily Au
Julie Groizeleau
Jacquelyn D. Rich
Yuefei Lou
Elise Granton
Laura K. Jennings
Larissa A. Singletary
Tara M. L. Winstone
Nathan M. Good
Roger E. Bumgarner
Michael F. Hynes
Manu Singh
Maria Silvina Stietz
Fiona S. L. Brinkman
Ayush Kumar
Ann Karen Cornelia Brassinga
Matthew R. Parsek
Boo Shan Tseng
Ian A. Lewis
Bryan G. Yipp
Justin L. MacCallum
Joe Jonathan Harrison
author_facet Henrik Almblad
Trevor E. Randall
Fanny Liu
Katherine Leblanc
Ryan A. Groves
Weerayuth Kittichotirat
Geoffrey L. Winsor
Nicolas Fournier
Emily Au
Julie Groizeleau
Jacquelyn D. Rich
Yuefei Lou
Elise Granton
Laura K. Jennings
Larissa A. Singletary
Tara M. L. Winstone
Nathan M. Good
Roger E. Bumgarner
Michael F. Hynes
Manu Singh
Maria Silvina Stietz
Fiona S. L. Brinkman
Ayush Kumar
Ann Karen Cornelia Brassinga
Matthew R. Parsek
Boo Shan Tseng
Ian A. Lewis
Bryan G. Yipp
Justin L. MacCallum
Joe Jonathan Harrison
author_sort Henrik Almblad
title Bacterial cyclic diguanylate signaling networks sense temperature
title_short Bacterial cyclic diguanylate signaling networks sense temperature
title_full Bacterial cyclic diguanylate signaling networks sense temperature
title_fullStr Bacterial cyclic diguanylate signaling networks sense temperature
title_full_unstemmed Bacterial cyclic diguanylate signaling networks sense temperature
title_sort bacterial cyclic diguanylate signaling networks sense temperature
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/6182b1bdedda46118764d49013acab00
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