Bacterial cyclic diguanylate signaling networks sense temperature
Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility, biofilm production and virulence. Here, the authors identify a thermosensitive enzyme that synthesizes c-di-GMP and modulates temperature-dependent motility, biofilm development and virulence in the opportunist...
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Nature Portfolio
2021
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oai:doaj.org-article:6182b1bdedda46118764d49013acab002021-12-02T14:23:03ZBacterial cyclic diguanylate signaling networks sense temperature10.1038/s41467-021-22176-22041-1723https://doaj.org/article/6182b1bdedda46118764d49013acab002021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22176-2https://doaj.org/toc/2041-1723Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility, biofilm production and virulence. Here, the authors identify a thermosensitive enzyme that synthesizes c-di-GMP and modulates temperature-dependent motility, biofilm development and virulence in the opportunistic pathogen Pseudomonas aeruginosa.Henrik AlmbladTrevor E. RandallFanny LiuKatherine LeblancRyan A. GrovesWeerayuth KittichotiratGeoffrey L. WinsorNicolas FournierEmily AuJulie GroizeleauJacquelyn D. RichYuefei LouElise GrantonLaura K. JenningsLarissa A. SingletaryTara M. L. WinstoneNathan M. GoodRoger E. BumgarnerMichael F. HynesManu SinghMaria Silvina StietzFiona S. L. BrinkmanAyush KumarAnn Karen Cornelia BrassingaMatthew R. ParsekBoo Shan TsengIan A. LewisBryan G. YippJustin L. MacCallumJoe Jonathan HarrisonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q Henrik Almblad Trevor E. Randall Fanny Liu Katherine Leblanc Ryan A. Groves Weerayuth Kittichotirat Geoffrey L. Winsor Nicolas Fournier Emily Au Julie Groizeleau Jacquelyn D. Rich Yuefei Lou Elise Granton Laura K. Jennings Larissa A. Singletary Tara M. L. Winstone Nathan M. Good Roger E. Bumgarner Michael F. Hynes Manu Singh Maria Silvina Stietz Fiona S. L. Brinkman Ayush Kumar Ann Karen Cornelia Brassinga Matthew R. Parsek Boo Shan Tseng Ian A. Lewis Bryan G. Yipp Justin L. MacCallum Joe Jonathan Harrison Bacterial cyclic diguanylate signaling networks sense temperature |
description |
Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility, biofilm production and virulence. Here, the authors identify a thermosensitive enzyme that synthesizes c-di-GMP and modulates temperature-dependent motility, biofilm development and virulence in the opportunistic pathogen Pseudomonas aeruginosa. |
format |
article |
author |
Henrik Almblad Trevor E. Randall Fanny Liu Katherine Leblanc Ryan A. Groves Weerayuth Kittichotirat Geoffrey L. Winsor Nicolas Fournier Emily Au Julie Groizeleau Jacquelyn D. Rich Yuefei Lou Elise Granton Laura K. Jennings Larissa A. Singletary Tara M. L. Winstone Nathan M. Good Roger E. Bumgarner Michael F. Hynes Manu Singh Maria Silvina Stietz Fiona S. L. Brinkman Ayush Kumar Ann Karen Cornelia Brassinga Matthew R. Parsek Boo Shan Tseng Ian A. Lewis Bryan G. Yipp Justin L. MacCallum Joe Jonathan Harrison |
author_facet |
Henrik Almblad Trevor E. Randall Fanny Liu Katherine Leblanc Ryan A. Groves Weerayuth Kittichotirat Geoffrey L. Winsor Nicolas Fournier Emily Au Julie Groizeleau Jacquelyn D. Rich Yuefei Lou Elise Granton Laura K. Jennings Larissa A. Singletary Tara M. L. Winstone Nathan M. Good Roger E. Bumgarner Michael F. Hynes Manu Singh Maria Silvina Stietz Fiona S. L. Brinkman Ayush Kumar Ann Karen Cornelia Brassinga Matthew R. Parsek Boo Shan Tseng Ian A. Lewis Bryan G. Yipp Justin L. MacCallum Joe Jonathan Harrison |
author_sort |
Henrik Almblad |
title |
Bacterial cyclic diguanylate signaling networks sense temperature |
title_short |
Bacterial cyclic diguanylate signaling networks sense temperature |
title_full |
Bacterial cyclic diguanylate signaling networks sense temperature |
title_fullStr |
Bacterial cyclic diguanylate signaling networks sense temperature |
title_full_unstemmed |
Bacterial cyclic diguanylate signaling networks sense temperature |
title_sort |
bacterial cyclic diguanylate signaling networks sense temperature |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/6182b1bdedda46118764d49013acab00 |
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