Pd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines

Sterically hindered unsaturated compounds are challenging substrates for asymmetric hydrogenation. Here, the authors report a palladium/chiral (bis)phosphine catalytic system that hydrogenates a number of hindered N-tosylimines with excellent enantioselectivitites.

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Autores principales:	Jianzhong Chen, Zhenfeng Zhang, Bowen Li, Feilong Li, Yulin Wang, Min Zhao, Ilya D. Gridnev, Tsuneo Imamoto, Wanbin Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/61887082b7564dc1b11a43ae2c800e82
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spelling	oai:doaj.org-article:61887082b7564dc1b11a43ae2c800e822021-12-02T17:32:45ZPd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines10.1038/s41467-018-07462-w2041-1723https://doaj.org/article/61887082b7564dc1b11a43ae2c800e822018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07462-whttps://doaj.org/toc/2041-1723Sterically hindered unsaturated compounds are challenging substrates for asymmetric hydrogenation. Here, the authors report a palladium/chiral (bis)phosphine catalytic system that hydrogenates a number of hindered N-tosylimines with excellent enantioselectivitites.Jianzhong ChenZhenfeng ZhangBowen LiFeilong LiYulin WangMin ZhaoIlya D. GridnevTsuneo ImamotoWanbin ZhangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jianzhong Chen Zhenfeng Zhang Bowen Li Feilong Li Yulin Wang Min Zhao Ilya D. Gridnev Tsuneo Imamoto Wanbin Zhang Pd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines
description	Sterically hindered unsaturated compounds are challenging substrates for asymmetric hydrogenation. Here, the authors report a palladium/chiral (bis)phosphine catalytic system that hydrogenates a number of hindered N-tosylimines with excellent enantioselectivitites.
format	article
author	Jianzhong Chen Zhenfeng Zhang Bowen Li Feilong Li Yulin Wang Min Zhao Ilya D. Gridnev Tsuneo Imamoto Wanbin Zhang
author_facet	Jianzhong Chen Zhenfeng Zhang Bowen Li Feilong Li Yulin Wang Min Zhao Ilya D. Gridnev Tsuneo Imamoto Wanbin Zhang
author_sort	Jianzhong Chen
title	Pd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines
title_short	Pd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines
title_full	Pd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines
title_fullStr	Pd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines
title_full_unstemmed	Pd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines
title_sort	pd(oac)2-catalyzed asymmetric hydrogenation of sterically hindered n-tosylimines
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/61887082b7564dc1b11a43ae2c800e82
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Pd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines

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