PARP Inhibitors and Haematological Malignancies—Friend or Foe?
Since their introduction several years ago, poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) have become the standard of care for breast and gynaecological cancers with <i>BRCA</i> gene mutations. Given that PARPi act by exploiting defective DNA repair mechanisms within tumour cell...
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Autores principales: | Kathryn A. Skelding, Lisa F. Lincz |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/618911a1190e402aa4b388aa486c5418 |
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