Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer

E3 ubiquitin ligases regulate biological functions by ubiquitinating defined substrate proteins but overlapping specificities complicate the identification of E3-substrate relationships. Here, the authors construct an orthogonal UB transfer cascade and identify specific substrates of the E3 enzyme E...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yiyang Wang, Xianpeng Liu, Li Zhou, Duc Duong, Karan Bhuripanyo, Bo Zhao, Han Zhou, Ruochuan Liu, Yingtao Bi, Hiroaki Kiyokawa, Jun Yin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/618a294ce3c64f68ae20e405e16ee8b0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:618a294ce3c64f68ae20e405e16ee8b0
record_format	dspace
spelling	oai:doaj.org-article:618a294ce3c64f68ae20e405e16ee8b02021-12-02T14:40:48ZIdentifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer10.1038/s41467-017-01974-72041-1723https://doaj.org/article/618a294ce3c64f68ae20e405e16ee8b02017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01974-7https://doaj.org/toc/2041-1723E3 ubiquitin ligases regulate biological functions by ubiquitinating defined substrate proteins but overlapping specificities complicate the identification of E3-substrate relationships. Here, the authors construct an orthogonal UB transfer cascade and identify specific substrates of the E3 enzyme E6AP.Yiyang WangXianpeng LiuLi ZhouDuc DuongKaran BhuripanyoBo ZhaoHan ZhouRuochuan LiuYingtao BiHiroaki KiyokawaJun YinNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yiyang Wang Xianpeng Liu Li Zhou Duc Duong Karan Bhuripanyo Bo Zhao Han Zhou Ruochuan Liu Yingtao Bi Hiroaki Kiyokawa Jun Yin Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer
description	E3 ubiquitin ligases regulate biological functions by ubiquitinating defined substrate proteins but overlapping specificities complicate the identification of E3-substrate relationships. Here, the authors construct an orthogonal UB transfer cascade and identify specific substrates of the E3 enzyme E6AP.
format	article
author	Yiyang Wang Xianpeng Liu Li Zhou Duc Duong Karan Bhuripanyo Bo Zhao Han Zhou Ruochuan Liu Yingtao Bi Hiroaki Kiyokawa Jun Yin
author_facet	Yiyang Wang Xianpeng Liu Li Zhou Duc Duong Karan Bhuripanyo Bo Zhao Han Zhou Ruochuan Liu Yingtao Bi Hiroaki Kiyokawa Jun Yin
author_sort	Yiyang Wang
title	Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer
title_short	Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer
title_full	Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer
title_fullStr	Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer
title_full_unstemmed	Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer
title_sort	identifying the ubiquitination targets of e6ap by orthogonal ubiquitin transfer
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/618a294ce3c64f68ae20e405e16ee8b0
work_keys_str_mv	AT yiyangwang identifyingtheubiquitinationtargetsofe6apbyorthogonalubiquitintransfer AT xianpengliu identifyingtheubiquitinationtargetsofe6apbyorthogonalubiquitintransfer AT lizhou identifyingtheubiquitinationtargetsofe6apbyorthogonalubiquitintransfer AT ducduong identifyingtheubiquitinationtargetsofe6apbyorthogonalubiquitintransfer AT karanbhuripanyo identifyingtheubiquitinationtargetsofe6apbyorthogonalubiquitintransfer AT bozhao identifyingtheubiquitinationtargetsofe6apbyorthogonalubiquitintransfer AT hanzhou identifyingtheubiquitinationtargetsofe6apbyorthogonalubiquitintransfer AT ruochuanliu identifyingtheubiquitinationtargetsofe6apbyorthogonalubiquitintransfer AT yingtaobi identifyingtheubiquitinationtargetsofe6apbyorthogonalubiquitintransfer AT hiroakikiyokawa identifyingtheubiquitinationtargetsofe6apbyorthogonalubiquitintransfer AT junyin identifyingtheubiquitinationtargetsofe6apbyorthogonalubiquitintransfer
_version_	1718390114100445184

Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer

Ejemplares similares