BLM helicase suppresses recombination at G-quadruplex motifs in transcribed genes
Bloom syndrome is characterized by high levels of sister chromatid exchanges (SCEs). Here, the authors use single-cell DNA template strand-sequencing to map SCEs in patient cells, and propose that the BLM helicase protects the genome against unwanted recombination at sites of G-quadruplex structures...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
|
| Subjects: | |
| Online Access: | https://doaj.org/article/618abfc1bc384381bf8da07ccfc3f7a1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|