Peculiar features of the clinical course of reflux disease in diabetic patients

Aim. To elucidate peculiar features of the clinical course of gastroesophageal reflux disease (GERD) in patients with type 1 and 2 diabetes mellitus(DM1 and DM2). Materials and methods. The study included 258 patients (68 DM and 190 DM2) undergoing 24-hour pH-metry, gastric and oesophageal endosco...

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Autores principales:	Natalya Vyacheslavovna Korneeva, Yury Leonidovich Fedorchenko
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2011
Materias:	gastroesophageal reflux disease oesophagitis diabetes mellitus Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/6198b0b0859c4a23b2e14807ddffc005
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spelling	oai:doaj.org-article:6198b0b0859c4a23b2e14807ddffc0052021-11-14T09:00:16ZPeculiar features of the clinical course of reflux disease in diabetic patients2072-03512072-037810.14341/2072-0351-5821https://doaj.org/article/6198b0b0859c4a23b2e14807ddffc0052011-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5821https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To elucidate peculiar features of the clinical course of gastroesophageal reflux disease (GERD) in patients with type 1 and 2 diabetes mellitus(DM1 and DM2). Materials and methods. The study included 258 patients (68 DM and 190 DM2) undergoing 24-hour pH-metry, gastric and oesophageal endoscopy,and evaluation of H.pylori (Hp) infestation. Results. Based on the results of pH-metry and complaints of the patients, GERD was diagnosed in 23.5 and 33.6% of DM1 and DM2 patients respectively.GERD in DM patients is frequently asymptomatic, with fewer complaints of oesophageal problems but more pronounced endoscopic changesin patients with GERD alone. Patients with GERD + DM more frequently present with erosive oesophagitis and oesophageal ulcers than those withGERD without DM. Patients with GERD + DM are characterized by a higher occurrence of H.pylori in gastric mucosa than patients with DM alone. Conclusion. GERD is a frequent pathology in DM1 and DM1 patients characterized by a peculiar, frequently asymptotic, clinical course; it requiresthorough attention of endocrinologists and gastroenterologists.Natalya Vyacheslavovna KorneevaYury Leonidovich FedorchenkoEndocrinology Research Centrearticlegastroesophageal reflux diseaseoesophagitisdiabetes mellitusNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 14, Iss 4, Pp 71-74 (2011)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	gastroesophageal reflux disease oesophagitis diabetes mellitus Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	gastroesophageal reflux disease oesophagitis diabetes mellitus Nutritional diseases. Deficiency diseases RC620-627 Natalya Vyacheslavovna Korneeva Yury Leonidovich Fedorchenko Peculiar features of the clinical course of reflux disease in diabetic patients
description	Aim. To elucidate peculiar features of the clinical course of gastroesophageal reflux disease (GERD) in patients with type 1 and 2 diabetes mellitus(DM1 and DM2). Materials and methods. The study included 258 patients (68 DM and 190 DM2) undergoing 24-hour pH-metry, gastric and oesophageal endoscopy,and evaluation of H.pylori (Hp) infestation. Results. Based on the results of pH-metry and complaints of the patients, GERD was diagnosed in 23.5 and 33.6% of DM1 and DM2 patients respectively.GERD in DM patients is frequently asymptomatic, with fewer complaints of oesophageal problems but more pronounced endoscopic changesin patients with GERD alone. Patients with GERD + DM more frequently present with erosive oesophagitis and oesophageal ulcers than those withGERD without DM. Patients with GERD + DM are characterized by a higher occurrence of H.pylori in gastric mucosa than patients with DM alone. Conclusion. GERD is a frequent pathology in DM1 and DM1 patients characterized by a peculiar, frequently asymptotic, clinical course; it requiresthorough attention of endocrinologists and gastroenterologists.
format	article
author	Natalya Vyacheslavovna Korneeva Yury Leonidovich Fedorchenko
author_facet	Natalya Vyacheslavovna Korneeva Yury Leonidovich Fedorchenko
author_sort	Natalya Vyacheslavovna Korneeva
title	Peculiar features of the clinical course of reflux disease in diabetic patients
title_short	Peculiar features of the clinical course of reflux disease in diabetic patients
title_full	Peculiar features of the clinical course of reflux disease in diabetic patients
title_fullStr	Peculiar features of the clinical course of reflux disease in diabetic patients
title_full_unstemmed	Peculiar features of the clinical course of reflux disease in diabetic patients
title_sort	peculiar features of the clinical course of reflux disease in diabetic patients
publisher	Endocrinology Research Centre
publishDate	2011
url	https://doaj.org/article/6198b0b0859c4a23b2e14807ddffc005
work_keys_str_mv	AT natalyavyacheslavovnakorneeva peculiarfeaturesoftheclinicalcourseofrefluxdiseaseindiabeticpatients AT yuryleonidovichfedorchenko peculiarfeaturesoftheclinicalcourseofrefluxdiseaseindiabeticpatients
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Peculiar features of the clinical course of reflux disease in diabetic patients

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