Various assisted bone regeneration in apicectomy defects systematic review and meta analysis
Introduction: In the endodontic surgery, the common applications are the procedures that apply regenerative methods. There are various methods that help in the regeneration after the endodontic root end cutting or apicectomy. The outcome of the apicectomy depends on the procedure and the material. H...
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Wolters Kluwer Medknow Publications
2021
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oai:doaj.org-article:619fb8c61df94ddf9899475e2421819d2021-11-19T12:15:51ZVarious assisted bone regeneration in apicectomy defects systematic review and meta analysis0975-740610.4103/jpbs.jpbs_375_21https://doaj.org/article/619fb8c61df94ddf9899475e2421819d2021-01-01T00:00:00Zhttp://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=6;spage=927;epage=932;aulast=Sumangalihttps://doaj.org/toc/0975-7406Introduction: In the endodontic surgery, the common applications are the procedures that apply regenerative methods. There are various methods that help in the regeneration after the endodontic root end cutting or apicectomy. The outcome of the apicectomy depends on the procedure and the material. Hence in the present study, we intend to conduct the systemic review and meta-analysis of the various assisted bone regeneration in apicectomy defects. Materials and Methods: The study was conducted by the online search of the data that included the studies for the regenerative procedure in the endodontic surgery in patients with various periapical pathologies. The data search engines were Scopus, Web of Science, Google Scholar, and PubMed. The risk of the bias was calculated. The study participants were divided into case and control groups. Case group had undergone the regenerative surgery for the persistent periapical lesions, while the control group had not undergone the regenerative surgery for the persistent periapical l. The clinical and the radiograph outcomes were compared between the control and the case groups. Meta-analysis was done and the subgroups were evaluated. Results: From a total of 1561 articles, only 11 were finalized for the study to conduct the meta-analysis. The bias was noted for majority of the studies most of which were clinical trials. It was observed that the regenerative methods used in the endodontic surgery have significantly improved the outcome. The application of the expanded polytetrafluoroethylene only has no significant effect; however, application of the autologous platelet concentrates or collagen membranes only had good outcomes. The combination of the materials showed a significant outcome than when applied alone. Conclusions: From this meta-analysis, it is evident that regenerative procedures are beneficial in the endodontic apicectomy procedures. The materials used in these procedures will augment the outcome. A better prognosis is expected if the combination of the materials is used.Ananad SumangaliRahul V C TiwariJeevana KolliparaMubashir Baig MirzaRajwinder Singh BrarAkshay M DhewaleWolters Kluwer Medknow Publicationsarticleapicoectomybone regeneration methodsmeta-analysisroot end cuttingPharmacy and materia medicaRS1-441Analytical chemistryQD71-142ENJournal of Pharmacy and Bioallied Sciences, Vol 13, Iss 6, Pp 927-932 (2021) |
| institution |
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DOAJ |
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EN |
| topic |
apicoectomy bone regeneration methods meta-analysis root end cutting Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142 |
| spellingShingle |
apicoectomy bone regeneration methods meta-analysis root end cutting Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142 Ananad Sumangali Rahul V C Tiwari Jeevana Kollipara Mubashir Baig Mirza Rajwinder Singh Brar Akshay M Dhewale Various assisted bone regeneration in apicectomy defects systematic review and meta analysis |
| description |
Introduction: In the endodontic surgery, the common applications are the procedures that apply regenerative methods. There are various methods that help in the regeneration after the endodontic root end cutting or apicectomy. The outcome of the apicectomy depends on the procedure and the material. Hence in the present study, we intend to conduct the systemic review and meta-analysis of the various assisted bone regeneration in apicectomy defects. Materials and Methods: The study was conducted by the online search of the data that included the studies for the regenerative procedure in the endodontic surgery in patients with various periapical pathologies. The data search engines were Scopus, Web of Science, Google Scholar, and PubMed. The risk of the bias was calculated. The study participants were divided into case and control groups. Case group had undergone the regenerative surgery for the persistent periapical lesions, while the control group had not undergone the regenerative surgery for the persistent periapical l. The clinical and the radiograph outcomes were compared between the control and the case groups. Meta-analysis was done and the subgroups were evaluated. Results: From a total of 1561 articles, only 11 were finalized for the study to conduct the meta-analysis. The bias was noted for majority of the studies most of which were clinical trials. It was observed that the regenerative methods used in the endodontic surgery have significantly improved the outcome. The application of the expanded polytetrafluoroethylene only has no significant effect; however, application of the autologous platelet concentrates or collagen membranes only had good outcomes. The combination of the materials showed a significant outcome than when applied alone. Conclusions: From this meta-analysis, it is evident that regenerative procedures are beneficial in the endodontic apicectomy procedures. The materials used in these procedures will augment the outcome. A better prognosis is expected if the combination of the materials is used. |
| format |
article |
| author |
Ananad Sumangali Rahul V C Tiwari Jeevana Kollipara Mubashir Baig Mirza Rajwinder Singh Brar Akshay M Dhewale |
| author_facet |
Ananad Sumangali Rahul V C Tiwari Jeevana Kollipara Mubashir Baig Mirza Rajwinder Singh Brar Akshay M Dhewale |
| author_sort |
Ananad Sumangali |
| title |
Various assisted bone regeneration in apicectomy defects systematic review and meta analysis |
| title_short |
Various assisted bone regeneration in apicectomy defects systematic review and meta analysis |
| title_full |
Various assisted bone regeneration in apicectomy defects systematic review and meta analysis |
| title_fullStr |
Various assisted bone regeneration in apicectomy defects systematic review and meta analysis |
| title_full_unstemmed |
Various assisted bone regeneration in apicectomy defects systematic review and meta analysis |
| title_sort |
various assisted bone regeneration in apicectomy defects systematic review and meta analysis |
| publisher |
Wolters Kluwer Medknow Publications |
| publishDate |
2021 |
| url |
https://doaj.org/article/619fb8c61df94ddf9899475e2421819d |
| work_keys_str_mv |
AT ananadsumangali variousassistedboneregenerationinapicectomydefectssystematicreviewandmetaanalysis AT rahulvctiwari variousassistedboneregenerationinapicectomydefectssystematicreviewandmetaanalysis AT jeevanakollipara variousassistedboneregenerationinapicectomydefectssystematicreviewandmetaanalysis AT mubashirbaigmirza variousassistedboneregenerationinapicectomydefectssystematicreviewandmetaanalysis AT rajwindersinghbrar variousassistedboneregenerationinapicectomydefectssystematicreviewandmetaanalysis AT akshaymdhewale variousassistedboneregenerationinapicectomydefectssystematicreviewandmetaanalysis |
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