Uncovering transcriptional dark matter via gene annotation independent single-cell RNA sequencing analysis

Conventional single-cell RNA sequencing analysis rely on genome annotations that may be incomplete or inaccurate especially for understudied organisms. Here the authors present a bioinformatic tool that leverages single-cell data to uncover biologically relevant transcripts beyond the best available...

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Bibliographic Details
Main Authors: Michael F. Z. Wang, Madhav Mantri, Shao-Pei Chou, Gaetano J. Scuderi, David W. McKellar, Jonathan T. Butcher, Charles G. Danko, Iwijn De Vlaminck
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/61a7bc13e77e42f98fc57182ea58774c
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