Biocompatible Nanomaterials as an Emerging Technology in Reproductive Health; a Focus on the Male
A growing body of research has confirmed that nanoparticle (NP) systems can enhance delivery of therapeutic and imaging agents as well as prevent potentially damaging systemic exposure to these agents by modifying the kinetics of their release. With a wide choice of NP materials possessing different...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:61b23b65734045e3af1f2c5fc9fd21642021-11-11T07:50:15ZBiocompatible Nanomaterials as an Emerging Technology in Reproductive Health; a Focus on the Male1664-042X10.3389/fphys.2021.753686https://doaj.org/article/61b23b65734045e3af1f2c5fc9fd21642021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fphys.2021.753686/fullhttps://doaj.org/toc/1664-042XA growing body of research has confirmed that nanoparticle (NP) systems can enhance delivery of therapeutic and imaging agents as well as prevent potentially damaging systemic exposure to these agents by modifying the kinetics of their release. With a wide choice of NP materials possessing different properties and surface modification options with unique targeting agents, bespoke nanosystems have been developed for applications varying from cancer therapeutics and genetic modification to cell imaging. Although there remain many challenges for the clinical application of nanoparticles, including toxicity within the reproductive system, some of these may be overcome with the recent development of biodegradable nanoparticles that offer increased biocompatibility. In recognition of this potential, this review seeks to present recent NP research with a focus on the exciting possibilities posed by the application of biocompatible nanomaterials within the fields of male reproductive medicine, health, and research.Barbara FraserBarbara FraserAlexandra E. PetersAlexandra E. PetersJessie M. SutherlandJessie M. SutherlandMingtao LiangMingtao LiangDiane RebourcetDiane RebourcetBrett NixonBrett NixonRobert J. AitkenRobert J. AitkenFrontiers Media S.A.articlenanomaterialsreproductive researchmale reproductive healthchemotherapyimagingPhysiologyQP1-981ENFrontiers in Physiology, Vol 12 (2021) |
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nanomaterials reproductive research male reproductive health chemotherapy imaging Physiology QP1-981 |
spellingShingle |
nanomaterials reproductive research male reproductive health chemotherapy imaging Physiology QP1-981 Barbara Fraser Barbara Fraser Alexandra E. Peters Alexandra E. Peters Jessie M. Sutherland Jessie M. Sutherland Mingtao Liang Mingtao Liang Diane Rebourcet Diane Rebourcet Brett Nixon Brett Nixon Robert J. Aitken Robert J. Aitken Biocompatible Nanomaterials as an Emerging Technology in Reproductive Health; a Focus on the Male |
description |
A growing body of research has confirmed that nanoparticle (NP) systems can enhance delivery of therapeutic and imaging agents as well as prevent potentially damaging systemic exposure to these agents by modifying the kinetics of their release. With a wide choice of NP materials possessing different properties and surface modification options with unique targeting agents, bespoke nanosystems have been developed for applications varying from cancer therapeutics and genetic modification to cell imaging. Although there remain many challenges for the clinical application of nanoparticles, including toxicity within the reproductive system, some of these may be overcome with the recent development of biodegradable nanoparticles that offer increased biocompatibility. In recognition of this potential, this review seeks to present recent NP research with a focus on the exciting possibilities posed by the application of biocompatible nanomaterials within the fields of male reproductive medicine, health, and research. |
format |
article |
author |
Barbara Fraser Barbara Fraser Alexandra E. Peters Alexandra E. Peters Jessie M. Sutherland Jessie M. Sutherland Mingtao Liang Mingtao Liang Diane Rebourcet Diane Rebourcet Brett Nixon Brett Nixon Robert J. Aitken Robert J. Aitken |
author_facet |
Barbara Fraser Barbara Fraser Alexandra E. Peters Alexandra E. Peters Jessie M. Sutherland Jessie M. Sutherland Mingtao Liang Mingtao Liang Diane Rebourcet Diane Rebourcet Brett Nixon Brett Nixon Robert J. Aitken Robert J. Aitken |
author_sort |
Barbara Fraser |
title |
Biocompatible Nanomaterials as an Emerging Technology in Reproductive Health; a Focus on the Male |
title_short |
Biocompatible Nanomaterials as an Emerging Technology in Reproductive Health; a Focus on the Male |
title_full |
Biocompatible Nanomaterials as an Emerging Technology in Reproductive Health; a Focus on the Male |
title_fullStr |
Biocompatible Nanomaterials as an Emerging Technology in Reproductive Health; a Focus on the Male |
title_full_unstemmed |
Biocompatible Nanomaterials as an Emerging Technology in Reproductive Health; a Focus on the Male |
title_sort |
biocompatible nanomaterials as an emerging technology in reproductive health; a focus on the male |
publisher |
Frontiers Media S.A. |
publishDate |
2021 |
url |
https://doaj.org/article/61b23b65734045e3af1f2c5fc9fd2164 |
work_keys_str_mv |
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