Palmitic acid increases apoptosis by mitochondrial pathway in hepatocytes with growth hormone deficiency
Objective To investigate the specific molecular mechanisms of palmitic acid (PA)-induced lipid deposition in cultured hepatocytes with knockdown of growth hormone receptor (GHR). Methods Hepatic L02 cells were treated with different concentrations of PA (0, 75, 150 and 300 μmol/L) for 12, 24, and 48...
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Autores principales: | WANG Yunting, ZHENG Xiaoya, CHEN Yue, QIAN Wenjie, WU Xun, REN Wei |
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Formato: | article |
Lenguaje: | ZH |
Publicado: |
Editorial Office of Journal of Third Military Medical University
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/61b303d66db0433485686ccce54028f5 |
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