Transcriptome-wide identification of transient RNA G-quadruplexes in human cells

In vivo existence of guanine-rich four-stranded RNA structures (G4-RNAs) has been a matter of debate. Here the authors developed a protocol, G4RP-seq, to capture and identify transcriptome-wide G4-RNA, providing insights into the formation of transient G4-RNA in live human cells.

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Autores principales:	Sunny Y. Yang, Pauline Lejault, Sandy Chevrier, Romain Boidot, A. Gordon Robertson, Judy M. Y. Wong, David Monchaud
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/61b9b8ce6219493191fa70ecc98a1fde
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spelling	oai:doaj.org-article:61b9b8ce6219493191fa70ecc98a1fde2021-12-02T15:34:15ZTranscriptome-wide identification of transient RNA G-quadruplexes in human cells10.1038/s41467-018-07224-82041-1723https://doaj.org/article/61b9b8ce6219493191fa70ecc98a1fde2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07224-8https://doaj.org/toc/2041-1723In vivo existence of guanine-rich four-stranded RNA structures (G4-RNAs) has been a matter of debate. Here the authors developed a protocol, G4RP-seq, to capture and identify transcriptome-wide G4-RNA, providing insights into the formation of transient G4-RNA in live human cells.Sunny Y. YangPauline LejaultSandy ChevrierRomain BoidotA. Gordon RobertsonJudy M. Y. WongDavid MonchaudNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sunny Y. Yang Pauline Lejault Sandy Chevrier Romain Boidot A. Gordon Robertson Judy M. Y. Wong David Monchaud Transcriptome-wide identification of transient RNA G-quadruplexes in human cells
description	In vivo existence of guanine-rich four-stranded RNA structures (G4-RNAs) has been a matter of debate. Here the authors developed a protocol, G4RP-seq, to capture and identify transcriptome-wide G4-RNA, providing insights into the formation of transient G4-RNA in live human cells.
format	article
author	Sunny Y. Yang Pauline Lejault Sandy Chevrier Romain Boidot A. Gordon Robertson Judy M. Y. Wong David Monchaud
author_facet	Sunny Y. Yang Pauline Lejault Sandy Chevrier Romain Boidot A. Gordon Robertson Judy M. Y. Wong David Monchaud
author_sort	Sunny Y. Yang
title	Transcriptome-wide identification of transient RNA G-quadruplexes in human cells
title_short	Transcriptome-wide identification of transient RNA G-quadruplexes in human cells
title_full	Transcriptome-wide identification of transient RNA G-quadruplexes in human cells
title_fullStr	Transcriptome-wide identification of transient RNA G-quadruplexes in human cells
title_full_unstemmed	Transcriptome-wide identification of transient RNA G-quadruplexes in human cells
title_sort	transcriptome-wide identification of transient rna g-quadruplexes in human cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/61b9b8ce6219493191fa70ecc98a1fde
work_keys_str_mv	AT sunnyyyang transcriptomewideidentificationoftransientrnagquadruplexesinhumancells AT paulinelejault transcriptomewideidentificationoftransientrnagquadruplexesinhumancells AT sandychevrier transcriptomewideidentificationoftransientrnagquadruplexesinhumancells AT romainboidot transcriptomewideidentificationoftransientrnagquadruplexesinhumancells AT agordonrobertson transcriptomewideidentificationoftransientrnagquadruplexesinhumancells AT judymywong transcriptomewideidentificationoftransientrnagquadruplexesinhumancells AT davidmonchaud transcriptomewideidentificationoftransientrnagquadruplexesinhumancells
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Transcriptome-wide identification of transient RNA G-quadruplexes in human cells

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