Pilus Adhesin RrgA Interacts with Complement Receptor 3, Thereby Affecting Macrophage Function and Systemic Pneumococcal Disease
ABSTRACT Pneumococcal pili have been shown to influence pneumococcal colonization, disease development, and the inflammatory response in mice. The role of the pilus-associated RrgA adhesin in pneumococcal interactions with murine and human macrophages was investigated. Expression of pili with RrgA e...
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Autores principales: | Sofia Orrskog, Samuli Rounioja, Tiziana Spadafina, Marilena Gallotta, Martin Norman, Karina Hentrich, Stefan Fälker, Sofia Ygberg-Eriksson, Mike Hasenberg, Björn Johansson, Liisa M. Uotila, Carl G. Gahmberg, Michèle Barocchi, Matthias Gunzer, Staffan Normark, Birgitta Henriques-Normark |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/61bf47911139403a9c51ff45e75d9a80 |
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