Functional analysis of Hsp70 inhibitors.

The molecular chaperones of the Hsp70 family have been recognized as targets for anti-cancer therapy. Since several paralogs of Hsp70 proteins exist in cytosol, endoplasmic reticulum and mitochondria, we investigated which isoform needs to be down-regulated for reducing viability of cancer cells. Fo...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Rainer Schlecht, Sebastian R Scholz, Heike Dahmen, Ansgar Wegener, Christian Sirrenberg, Djordje Musil, Joerg Bomke, Hans-Michael Eggenweiler, Matthias P Mayer, Bernd Bukau
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
R
Q
Acceso en línea:https://doaj.org/article/61d0e4e74a9e4efa87d2fb910f1f8022
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!