Lung colonization by Aspergillus fumigatus is controlled by ZNF77

Aspergillus fumigatus regularly colonises the lungs but in the context of respiratory disease can be associated with increased pathology. Here the authors show mutations in ZNF77 result in altered bronchial epithelial characteristics and enhanced fungal burden.

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Détails bibliographiques
Auteurs principaux:	Sara Gago, Nicola L. D. Overton, Nagwa Ben-Ghazzi, Lilyann Novak-Frazer, Nick D. Read, David W. Denning, Paul Bowyer
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2018
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/61d2471016bd4353b85a81e3a4a5f756
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id	oai:doaj.org-article:61d2471016bd4353b85a81e3a4a5f756
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spelling	oai:doaj.org-article:61d2471016bd4353b85a81e3a4a5f7562021-12-02T14:40:31ZLung colonization by Aspergillus fumigatus is controlled by ZNF7710.1038/s41467-018-06148-72041-1723https://doaj.org/article/61d2471016bd4353b85a81e3a4a5f7562018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06148-7https://doaj.org/toc/2041-1723Aspergillus fumigatus regularly colonises the lungs but in the context of respiratory disease can be associated with increased pathology. Here the authors show mutations in ZNF77 result in altered bronchial epithelial characteristics and enhanced fungal burden.Sara GagoNicola L. D. OvertonNagwa Ben-GhazziLilyann Novak-FrazerNick D. ReadDavid W. DenningPaul BowyerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sara Gago Nicola L. D. Overton Nagwa Ben-Ghazzi Lilyann Novak-Frazer Nick D. Read David W. Denning Paul Bowyer Lung colonization by Aspergillus fumigatus is controlled by ZNF77
description	Aspergillus fumigatus regularly colonises the lungs but in the context of respiratory disease can be associated with increased pathology. Here the authors show mutations in ZNF77 result in altered bronchial epithelial characteristics and enhanced fungal burden.
format	article
author	Sara Gago Nicola L. D. Overton Nagwa Ben-Ghazzi Lilyann Novak-Frazer Nick D. Read David W. Denning Paul Bowyer
author_facet	Sara Gago Nicola L. D. Overton Nagwa Ben-Ghazzi Lilyann Novak-Frazer Nick D. Read David W. Denning Paul Bowyer
author_sort	Sara Gago
title	Lung colonization by Aspergillus fumigatus is controlled by ZNF77
title_short	Lung colonization by Aspergillus fumigatus is controlled by ZNF77
title_full	Lung colonization by Aspergillus fumigatus is controlled by ZNF77
title_fullStr	Lung colonization by Aspergillus fumigatus is controlled by ZNF77
title_full_unstemmed	Lung colonization by Aspergillus fumigatus is controlled by ZNF77
title_sort	lung colonization by aspergillus fumigatus is controlled by znf77
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/61d2471016bd4353b85a81e3a4a5f756
work_keys_str_mv	AT saragago lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 AT nicolaldoverton lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 AT nagwabenghazzi lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 AT lilyannnovakfrazer lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 AT nickdread lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 AT davidwdenning lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 AT paulbowyer lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77
_version_	1718390240255672320

Lung colonization by Aspergillus fumigatus is controlled by ZNF77

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