Lung colonization by Aspergillus fumigatus is controlled by ZNF77
Aspergillus fumigatus regularly colonises the lungs but in the context of respiratory disease can be associated with increased pathology. Here the authors show mutations in ZNF77 result in altered bronchial epithelial characteristics and enhanced fungal burden.
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Nature Portfolio
2018
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oai:doaj.org-article:61d2471016bd4353b85a81e3a4a5f7562021-12-02T14:40:31ZLung colonization by Aspergillus fumigatus is controlled by ZNF7710.1038/s41467-018-06148-72041-1723https://doaj.org/article/61d2471016bd4353b85a81e3a4a5f7562018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06148-7https://doaj.org/toc/2041-1723Aspergillus fumigatus regularly colonises the lungs but in the context of respiratory disease can be associated with increased pathology. Here the authors show mutations in ZNF77 result in altered bronchial epithelial characteristics and enhanced fungal burden.Sara GagoNicola L. D. OvertonNagwa Ben-GhazziLilyann Novak-FrazerNick D. ReadDavid W. DenningPaul BowyerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Sara Gago Nicola L. D. Overton Nagwa Ben-Ghazzi Lilyann Novak-Frazer Nick D. Read David W. Denning Paul Bowyer Lung colonization by Aspergillus fumigatus is controlled by ZNF77 |
description |
Aspergillus fumigatus regularly colonises the lungs but in the context of respiratory disease can be associated with increased pathology. Here the authors show mutations in ZNF77 result in altered bronchial epithelial characteristics and enhanced fungal burden. |
format |
article |
author |
Sara Gago Nicola L. D. Overton Nagwa Ben-Ghazzi Lilyann Novak-Frazer Nick D. Read David W. Denning Paul Bowyer |
author_facet |
Sara Gago Nicola L. D. Overton Nagwa Ben-Ghazzi Lilyann Novak-Frazer Nick D. Read David W. Denning Paul Bowyer |
author_sort |
Sara Gago |
title |
Lung colonization by Aspergillus fumigatus is controlled by ZNF77 |
title_short |
Lung colonization by Aspergillus fumigatus is controlled by ZNF77 |
title_full |
Lung colonization by Aspergillus fumigatus is controlled by ZNF77 |
title_fullStr |
Lung colonization by Aspergillus fumigatus is controlled by ZNF77 |
title_full_unstemmed |
Lung colonization by Aspergillus fumigatus is controlled by ZNF77 |
title_sort |
lung colonization by aspergillus fumigatus is controlled by znf77 |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/61d2471016bd4353b85a81e3a4a5f756 |
work_keys_str_mv |
AT saragago lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 AT nicolaldoverton lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 AT nagwabenghazzi lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 AT lilyannnovakfrazer lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 AT nickdread lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 AT davidwdenning lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 AT paulbowyer lungcolonizationbyaspergillusfumigatusiscontrolledbyznf77 |
_version_ |
1718390240255672320 |