Modern Concepts of Clinical and Diagnostic Criteria for Premature Ovarian Failure (Literature Review)

Premature ovarian insufficiency (POI) is a life-changing diagnosis with profound physical and psychological consequences. POI, defined as amenorrhea due to the loss of ovarian function before 40 years of age, can occur spontaneously or be secondary to medical therapies. POI is associated with cardio...

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Autores principales: M. D. Salimova, Ya. G. Nadelyaeva, I. N. Danusevich
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2021
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spelling oai:doaj.org-article:61d5b82ce2474599a0476ce8c008987b2021-11-23T06:14:45ZModern Concepts of Clinical and Diagnostic Criteria for Premature Ovarian Failure (Literature Review)2541-94202587-959610.29413/ABS.2020-5.6.5https://doaj.org/article/61d5b82ce2474599a0476ce8c008987b2021-01-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/2494https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Premature ovarian insufficiency (POI) is a life-changing diagnosis with profound physical and psychological consequences. POI, defined as amenorrhea due to the loss of ovarian function before 40 years of age, can occur spontaneously or be secondary to medical therapies. POI is associated with cardiovascular morbidity, osteoporosis and premature mortality. General practitioners play an important role in the evaluation and long-term management of women with POI. Before getting to the gynecologist, more than 50 % of women, on average, turn to three different specialists. Success of early diagnosis, possibility of timely prescription of hormone therapy, and monitoring of the long-term effects of hypoestrogenism depend on the general practitioner’s knowledge of this pathology. The purpose of this review was to systematize the available data on modern clinical diagnostic criteria for POI, for the early detection and prevention of reproductive losses, as well as improving the quality of life of women. An information search was carried out using Internet resources (PubMed, Web of Science, eLibrary.Ru), literary sources for the period 2015–2019 were analyzed. As a result of the analysis of the literature data, a step-by-step diagnosis of pathology was described, the main shortcomings of the main marker for assessing ovarian function – folliclestimulating hormone – were identified and listed. And also the advantages of  anti-Müllerian hormone in the early diagnosis of ovarian insufficiency are considered.M. D. SalimovaYa. G. NadelyaevaI. N. DanusevichScientific Сentre for Family Health and Human Reproduction Problemsarticlepremature ovarian failurepremature ovarian insufficiencyovarian reservediagnosis of poiinfertilityamenorrheaanti-müllerian hormonefollicle-stimulating hormoneScienceQRUActa Biomedica Scientifica, Vol 5, Iss 6, Pp 42-50 (2021)
institution DOAJ
collection DOAJ
language RU
topic premature ovarian failure
premature ovarian insufficiency
ovarian reserve
diagnosis of poi
infertility
amenorrhea
anti-müllerian hormone
follicle-stimulating hormone
Science
Q
spellingShingle premature ovarian failure
premature ovarian insufficiency
ovarian reserve
diagnosis of poi
infertility
amenorrhea
anti-müllerian hormone
follicle-stimulating hormone
Science
Q
M. D. Salimova
Ya. G. Nadelyaeva
I. N. Danusevich
Modern Concepts of Clinical and Diagnostic Criteria for Premature Ovarian Failure (Literature Review)
description Premature ovarian insufficiency (POI) is a life-changing diagnosis with profound physical and psychological consequences. POI, defined as amenorrhea due to the loss of ovarian function before 40 years of age, can occur spontaneously or be secondary to medical therapies. POI is associated with cardiovascular morbidity, osteoporosis and premature mortality. General practitioners play an important role in the evaluation and long-term management of women with POI. Before getting to the gynecologist, more than 50 % of women, on average, turn to three different specialists. Success of early diagnosis, possibility of timely prescription of hormone therapy, and monitoring of the long-term effects of hypoestrogenism depend on the general practitioner’s knowledge of this pathology. The purpose of this review was to systematize the available data on modern clinical diagnostic criteria for POI, for the early detection and prevention of reproductive losses, as well as improving the quality of life of women. An information search was carried out using Internet resources (PubMed, Web of Science, eLibrary.Ru), literary sources for the period 2015–2019 were analyzed. As a result of the analysis of the literature data, a step-by-step diagnosis of pathology was described, the main shortcomings of the main marker for assessing ovarian function – folliclestimulating hormone – were identified and listed. And also the advantages of  anti-Müllerian hormone in the early diagnosis of ovarian insufficiency are considered.
format article
author M. D. Salimova
Ya. G. Nadelyaeva
I. N. Danusevich
author_facet M. D. Salimova
Ya. G. Nadelyaeva
I. N. Danusevich
author_sort M. D. Salimova
title Modern Concepts of Clinical and Diagnostic Criteria for Premature Ovarian Failure (Literature Review)
title_short Modern Concepts of Clinical and Diagnostic Criteria for Premature Ovarian Failure (Literature Review)
title_full Modern Concepts of Clinical and Diagnostic Criteria for Premature Ovarian Failure (Literature Review)
title_fullStr Modern Concepts of Clinical and Diagnostic Criteria for Premature Ovarian Failure (Literature Review)
title_full_unstemmed Modern Concepts of Clinical and Diagnostic Criteria for Premature Ovarian Failure (Literature Review)
title_sort modern concepts of clinical and diagnostic criteria for premature ovarian failure (literature review)
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2021
url https://doaj.org/article/61d5b82ce2474599a0476ce8c008987b
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