Novel Structures of Type 1 Glyceraldehyde-3-phosphate Dehydrogenase from <i>Escherichia coli</i> Provide New Insights into the Mechanism of Generation of 1,3-Bisphosphoglyceric Acid
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a highly conserved enzyme involved in the ubiquitous process of glycolysis and presents a loop (residues 208–215 of <i>Escherichia coli</i> GAPDH) in two alternative conformations (I and II). It is uncertain what triggers this loop rear...
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Main Authors: | Li Zhang, Meiruo Liu, Luyao Bao, Kristina I. Boström, Yucheng Yao, Jixi Li, Shaohua Gu, Chaoneng Ji |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Online Access: | https://doaj.org/article/61d9c95b9c3c444bbfb3e5553c702d76 |
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