Histo-blood group gene polymorphisms as potential genetic modifiers of infection and cystic fibrosis lung disease severity.

Histo-blood group gene polymorphisms as potential genetic modifiers of infection and cystic fibrosis lung disease severity.

<h4>Background</h4>The pulmonary phenotype in cystic fibrosis (CF) is variable; thus, environmental and genetic factors likely contribute to clinical heterogeneity. We hypothesized that genetically determined ABO histo-blood group antigen (ABH) differences in glycosylation may lead to di...

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Autores principales: Jennifer L Taylor-Cousar, Maimoona A Zariwala, Lauranell H Burch, Rhonda G Pace, Mitchell L Drumm, Hollin Calloway, Haiying Fan, Brent W Weston, Fred A Wright, Michael R Knowles, Gene Modifier Study Group
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/61df60e10ca048179da07334e6973944
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