A 50 Hz magnetic field affects hemodynamics, ECG and vascular endothelial function in healthy adults: A pilot randomized controlled trial.

Application of exposure to 50/60 Hz magnetic fields (MFs) has been conducted in the treatment of muscle pain and fatigue mainly in Japan. However, whether MFs could increase blood flow leading to muscle fatigue recovery has not been sufficiently tested. We investigated the acute effects of a 50 Hz s...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hideyuki Okano, Akikatsu Fujimura, Tsukasa Kondo, Ilkka Laakso, Hiromi Ishiwatari, Keiichi Watanuki
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/61e2613726cc4744b1164bf9b525b55a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:61e2613726cc4744b1164bf9b525b55a
record_format	dspace
spelling	oai:doaj.org-article:61e2613726cc4744b1164bf9b525b55a2021-12-02T20:15:14ZA 50 Hz magnetic field affects hemodynamics, ECG and vascular endothelial function in healthy adults: A pilot randomized controlled trial.1932-620310.1371/journal.pone.0255242https://doaj.org/article/61e2613726cc4744b1164bf9b525b55a2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0255242https://doaj.org/toc/1932-6203Application of exposure to 50/60 Hz magnetic fields (MFs) has been conducted in the treatment of muscle pain and fatigue mainly in Japan. However, whether MFs could increase blood flow leading to muscle fatigue recovery has not been sufficiently tested. We investigated the acute effects of a 50 Hz sinusoidal MF at Bmax 180 mT on hemodynamics, electrocardiogram, and vascular endothelial function in healthy young men. Three types of regional exposures to a 50 Hz MF, i.e., forearm, upper arm, or neck exposure to MF were performed. Participants who received three types of real MF exposures had significantly increased ulnar arterial blood flow velocity compared to the sham exposures. Furthermore, after muscle loading exercise, MF exposure recovered hemoglobin oxygenation index values faster and higher than sham exposure from the loading condition. Moreover, participants who received real MF exposure in the neck region had significantly increased parasympathetic high-frequency activity relative to the sham exposure. The MF exposure in the upper arm region significantly increased the brachial artery flow-mediated dilation compared to the sham exposure. Computer simulations of induced in situ electric fields indicated that the order-of-magnitude estimates of the peak values were 100-500 mV/m, depending on the exposure conditions. This study provides the first evidence that a 50 Hz MF can activate parasympathetic activity and thereby lead to increase vasodilation and blood flow via a nitric oxide-dependent mechanism. Trial registration: UMIN Clinical Trial Registry (CTR) UMIN000038834. The authors confirm that all ongoing and related trials for this drug/intervention are registered.Hideyuki OkanoAkikatsu FujimuraTsukasa KondoIlkka LaaksoHiromi IshiwatariKeiichi WatanukiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0255242 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hideyuki Okano Akikatsu Fujimura Tsukasa Kondo Ilkka Laakso Hiromi Ishiwatari Keiichi Watanuki A 50 Hz magnetic field affects hemodynamics, ECG and vascular endothelial function in healthy adults: A pilot randomized controlled trial.
description	Application of exposure to 50/60 Hz magnetic fields (MFs) has been conducted in the treatment of muscle pain and fatigue mainly in Japan. However, whether MFs could increase blood flow leading to muscle fatigue recovery has not been sufficiently tested. We investigated the acute effects of a 50 Hz sinusoidal MF at Bmax 180 mT on hemodynamics, electrocardiogram, and vascular endothelial function in healthy young men. Three types of regional exposures to a 50 Hz MF, i.e., forearm, upper arm, or neck exposure to MF were performed. Participants who received three types of real MF exposures had significantly increased ulnar arterial blood flow velocity compared to the sham exposures. Furthermore, after muscle loading exercise, MF exposure recovered hemoglobin oxygenation index values faster and higher than sham exposure from the loading condition. Moreover, participants who received real MF exposure in the neck region had significantly increased parasympathetic high-frequency activity relative to the sham exposure. The MF exposure in the upper arm region significantly increased the brachial artery flow-mediated dilation compared to the sham exposure. Computer simulations of induced in situ electric fields indicated that the order-of-magnitude estimates of the peak values were 100-500 mV/m, depending on the exposure conditions. This study provides the first evidence that a 50 Hz MF can activate parasympathetic activity and thereby lead to increase vasodilation and blood flow via a nitric oxide-dependent mechanism. Trial registration: UMIN Clinical Trial Registry (CTR) UMIN000038834. The authors confirm that all ongoing and related trials for this drug/intervention are registered.
format	article
author	Hideyuki Okano Akikatsu Fujimura Tsukasa Kondo Ilkka Laakso Hiromi Ishiwatari Keiichi Watanuki
author_facet	Hideyuki Okano Akikatsu Fujimura Tsukasa Kondo Ilkka Laakso Hiromi Ishiwatari Keiichi Watanuki
author_sort	Hideyuki Okano
title	A 50 Hz magnetic field affects hemodynamics, ECG and vascular endothelial function in healthy adults: A pilot randomized controlled trial.
title_short	A 50 Hz magnetic field affects hemodynamics, ECG and vascular endothelial function in healthy adults: A pilot randomized controlled trial.
title_full	A 50 Hz magnetic field affects hemodynamics, ECG and vascular endothelial function in healthy adults: A pilot randomized controlled trial.
title_fullStr	A 50 Hz magnetic field affects hemodynamics, ECG and vascular endothelial function in healthy adults: A pilot randomized controlled trial.
title_full_unstemmed	A 50 Hz magnetic field affects hemodynamics, ECG and vascular endothelial function in healthy adults: A pilot randomized controlled trial.
title_sort	50 hz magnetic field affects hemodynamics, ecg and vascular endothelial function in healthy adults: a pilot randomized controlled trial.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/61e2613726cc4744b1164bf9b525b55a
work_keys_str_mv	AT hideyukiokano a50hzmagneticfieldaffectshemodynamicsecgandvascularendothelialfunctioninhealthyadultsapilotrandomizedcontrolledtrial AT akikatsufujimura a50hzmagneticfieldaffectshemodynamicsecgandvascularendothelialfunctioninhealthyadultsapilotrandomizedcontrolledtrial AT tsukasakondo a50hzmagneticfieldaffectshemodynamicsecgandvascularendothelialfunctioninhealthyadultsapilotrandomizedcontrolledtrial AT ilkkalaakso a50hzmagneticfieldaffectshemodynamicsecgandvascularendothelialfunctioninhealthyadultsapilotrandomizedcontrolledtrial AT hiromiishiwatari a50hzmagneticfieldaffectshemodynamicsecgandvascularendothelialfunctioninhealthyadultsapilotrandomizedcontrolledtrial AT keiichiwatanuki a50hzmagneticfieldaffectshemodynamicsecgandvascularendothelialfunctioninhealthyadultsapilotrandomizedcontrolledtrial AT hideyukiokano 50hzmagneticfieldaffectshemodynamicsecgandvascularendothelialfunctioninhealthyadultsapilotrandomizedcontrolledtrial AT akikatsufujimura 50hzmagneticfieldaffectshemodynamicsecgandvascularendothelialfunctioninhealthyadultsapilotrandomizedcontrolledtrial AT tsukasakondo 50hzmagneticfieldaffectshemodynamicsecgandvascularendothelialfunctioninhealthyadultsapilotrandomizedcontrolledtrial AT ilkkalaakso 50hzmagneticfieldaffectshemodynamicsecgandvascularendothelialfunctioninhealthyadultsapilotrandomizedcontrolledtrial AT hiromiishiwatari 50hzmagneticfieldaffectshemodynamicsecgandvascularendothelialfunctioninhealthyadultsapilotrandomizedcontrolledtrial AT keiichiwatanuki 50hzmagneticfieldaffectshemodynamicsecgandvascularendothelialfunctioninhealthyadultsapilotrandomizedcontrolledtrial
_version_	1718374584768528384

A 50 Hz magnetic field affects hemodynamics, ECG and vascular endothelial function in healthy adults: A pilot randomized controlled trial.

Ejemplares similares