Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry
Imaging of neuronal activity across distant brain regions is challenging. Here, the authors introduce a two-photon microscope with two independently controlled scan engines, and demonstrate calcium imaging with subcellular resolution in brain regions up to 7 mm apart simultaneously.
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Nature Portfolio
2021
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oai:doaj.org-article:61e2b203f08348f7bc349521ead6e6c72021-11-21T12:35:25ZDiesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry10.1038/s41467-021-26736-42041-1723https://doaj.org/article/61e2b203f08348f7bc349521ead6e6c72021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26736-4https://doaj.org/toc/2041-1723Imaging of neuronal activity across distant brain regions is challenging. Here, the authors introduce a two-photon microscope with two independently controlled scan engines, and demonstrate calcium imaging with subcellular resolution in brain regions up to 7 mm apart simultaneously.Che-Hang YuJeffrey N. StirmanYiyi YuRiichiro HiraSpencer L. SmithNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021) |
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Science Q Che-Hang Yu Jeffrey N. Stirman Yiyi Yu Riichiro Hira Spencer L. Smith Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry |
description |
Imaging of neuronal activity across distant brain regions is challenging. Here, the authors introduce a two-photon microscope with two independently controlled scan engines, and demonstrate calcium imaging with subcellular resolution in brain regions up to 7 mm apart simultaneously. |
format |
article |
author |
Che-Hang Yu Jeffrey N. Stirman Yiyi Yu Riichiro Hira Spencer L. Smith |
author_facet |
Che-Hang Yu Jeffrey N. Stirman Yiyi Yu Riichiro Hira Spencer L. Smith |
author_sort |
Che-Hang Yu |
title |
Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry |
title_short |
Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry |
title_full |
Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry |
title_fullStr |
Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry |
title_full_unstemmed |
Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry |
title_sort |
diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/61e2b203f08348f7bc349521ead6e6c7 |
work_keys_str_mv |
AT chehangyu diesel2pmesoscopewithdualindependentscanenginesforflexiblecaptureofdynamicsindistributedneuralcircuitry AT jeffreynstirman diesel2pmesoscopewithdualindependentscanenginesforflexiblecaptureofdynamicsindistributedneuralcircuitry AT yiyiyu diesel2pmesoscopewithdualindependentscanenginesforflexiblecaptureofdynamicsindistributedneuralcircuitry AT riichirohira diesel2pmesoscopewithdualindependentscanenginesforflexiblecaptureofdynamicsindistributedneuralcircuitry AT spencerlsmith diesel2pmesoscopewithdualindependentscanenginesforflexiblecaptureofdynamicsindistributedneuralcircuitry |
_version_ |
1718418886466994176 |