Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry

Imaging of neuronal activity across distant brain regions is challenging. Here, the authors introduce a two-photon microscope with two independently controlled scan engines, and demonstrate calcium imaging with subcellular resolution in brain regions up to 7 mm apart simultaneously.

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Autores principales: Che-Hang Yu, Jeffrey N. Stirman, Yiyi Yu, Riichiro Hira, Spencer L. Smith
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/61e2b203f08348f7bc349521ead6e6c7
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spelling oai:doaj.org-article:61e2b203f08348f7bc349521ead6e6c72021-11-21T12:35:25ZDiesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry10.1038/s41467-021-26736-42041-1723https://doaj.org/article/61e2b203f08348f7bc349521ead6e6c72021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26736-4https://doaj.org/toc/2041-1723Imaging of neuronal activity across distant brain regions is challenging. Here, the authors introduce a two-photon microscope with two independently controlled scan engines, and demonstrate calcium imaging with subcellular resolution in brain regions up to 7 mm apart simultaneously.Che-Hang YuJeffrey N. StirmanYiyi YuRiichiro HiraSpencer L. SmithNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Che-Hang Yu
Jeffrey N. Stirman
Yiyi Yu
Riichiro Hira
Spencer L. Smith
Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry
description Imaging of neuronal activity across distant brain regions is challenging. Here, the authors introduce a two-photon microscope with two independently controlled scan engines, and demonstrate calcium imaging with subcellular resolution in brain regions up to 7 mm apart simultaneously.
format article
author Che-Hang Yu
Jeffrey N. Stirman
Yiyi Yu
Riichiro Hira
Spencer L. Smith
author_facet Che-Hang Yu
Jeffrey N. Stirman
Yiyi Yu
Riichiro Hira
Spencer L. Smith
author_sort Che-Hang Yu
title Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry
title_short Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry
title_full Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry
title_fullStr Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry
title_full_unstemmed Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry
title_sort diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/61e2b203f08348f7bc349521ead6e6c7
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AT jeffreynstirman diesel2pmesoscopewithdualindependentscanenginesforflexiblecaptureofdynamicsindistributedneuralcircuitry
AT yiyiyu diesel2pmesoscopewithdualindependentscanenginesforflexiblecaptureofdynamicsindistributedneuralcircuitry
AT riichirohira diesel2pmesoscopewithdualindependentscanenginesforflexiblecaptureofdynamicsindistributedneuralcircuitry
AT spencerlsmith diesel2pmesoscopewithdualindependentscanenginesforflexiblecaptureofdynamicsindistributedneuralcircuitry
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