Inflammatory Biomarkers Are Associated With a Decline in Functional Status at Discharge in Children With Acute Respiratory Failure: An Exploratory Analysis

OBJECTIVES:. To evaluate the link between early acute respiratory failure and functional morbidity in survivors using the plasma biomarkers interleukin-8, interleukin-1 receptor antagonist, thrombomodulin, and plasminogen activator inhibitor-1. We hypothesized that children with acute respiratory fa...

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Main Authors: Erin F. Carlton, MD, MSc, Heidi M. Weeks, PhD, Mary K. Dahmer, PhD, Michael W. Quasney, MD, PhD, Anil Sapru, MD, MAS, Martha A.Q. Curley, PhD, RN, Heidi R. Flori, MD, for the BALI and RESTORE Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Heidi Flori, Michael W. Quasney, Mary K. Dahmer, Anil Sapru, Martha Curley, Michael A. Matthay, Scot T. Bateman, M. D. Berg, Santiago Borasino, G. Kris Bysani, Allison S. Cowl, Cindy Darnell Bowens, E. Vincent S. Faustino, Lori D. Fineman, A. J. Godshall, Ellie Hirshberg, Aileen L. Kirby, Gwenn E. McLaughlin, Shivanand Medar, Phineas P. Oren, James B. Schneider, Adam J. Schwarz, Thomas P. Shanley, Lauren R. Source, Edward J. Truemper, Michele A. Vander Heyden, Kim Wittmayer, Athena Zuppa, David Wypij, Martha A. Q. Curley, Geoffrey L. Allen, Derek C. Angus, Lisa A. Asaro, Judy A. Ascenzi, Ira M. Cheifetz, Brenda L. Dodson, Heidi R. Flori, Linda S. Franck, Rainer G. Gedeit, Mary Jo C. Grant, Andrea L. Harabin, Catherine Haskins-Kiefer, James H. Hertzog, Larissa Hutchins, Ruth M. Lebet, JoAnne E. Natale, Nagendra Polavarapu, Shari Simone, Lewis P. Singer, R. Scott Watson, Claire R. Wells
Format: article
Language:EN
Published: Wolters Kluwer 2021
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Online Access:https://doaj.org/article/61e7200c23f242228904d908a19129f5
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