<italic toggle="yes">Pseudomonas</italic> Biofilms, Cystic Fibrosis, and Phage: a Silver Lining?

ABSTRACT In contrast to usual laboratory conditions, most bacteria in the human body grow in biofilms. Encased in a structured matrix, many pathogens display heightened resistance to antibiotics. Pseudomonas aeruginosa lung infections in cystic fibrosis patients represent a prime example of the clin...

Full description

Saved in:
Bibliographic Details
Main Author: Harald Brüssow
Format: article
Language:EN
Published: American Society for Microbiology 2012
Subjects:
Online Access:https://doaj.org/article/61e7b195b2384a66949667fcdfb29c98
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:ABSTRACT In contrast to usual laboratory conditions, most bacteria in the human body grow in biofilms. Encased in a structured matrix, many pathogens display heightened resistance to antibiotics. Pseudomonas aeruginosa lung infections in cystic fibrosis patients represent a prime example of the clinical challenges that antibiotic resistance in biofilms can represent. In the March 6, 2012 issue of mBio, Colin Hill and his colleagues report on experiments that add to the evidence that Pseudomonas phages are a potential treatment option for these infections.