Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response.
Dopamine (DA) neurons of the midbrain are at risk to become affected by mitochondrial damage over time and mitochondrial defects have been frequently reported in Parkinson's disease (PD) patients. However, the causal contribution of adult-onset mitochondrial dysfunction to PD remains uncertain....
Guardado en:
Autores principales: | Roberta Filograna, Seungmin Lee, Katarína Tiklová, Mara Mennuni, Viktor Jonsson, Markus Ringnér, Linda Gillberg, Elena Sopova, Oleg Shupliakov, Camilla Koolmeister, Lars Olson, Thomas Perlmann, Nils-Göran Larsson |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/61f2fcf7bb484163bdda169112e41b0e |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development
por: Katarína Tiklová, et al.
Publicado: (2019) -
Midbrain Dopamine Neurons Defined by TrpV1 Modulate Psychomotor Behavior
por: Gian Pietro Serra, et al.
Publicado: (2021) -
The cost of obtaining rewards enhances the reward prediction error signal of midbrain dopamine neurons
por: Shingo Tanaka, et al.
Publicado: (2019) -
Mesopontine cholinergic inputs to midbrain dopamine neurons drive stress-induced depressive-like behaviors
por: Sebastian P. Fernandez, et al.
Publicado: (2018) -
TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons
por: Layal Maatouk, et al.
Publicado: (2018)