Clinical and imaging characteristics of orbital metastatic lesions among Egyptian patients
Mohammed A Eldesouky, Molham A Elbakary Oculoplastic Unit, Faculty of Medicine, Tanta University, Tanta, Egypt Purpose: The aim of the study was to review the demographic, clinical, and imaging features of Egyptian patients with orbital metastases.Methods: The study was a retrospective study of pa...
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| Formato: | article |
| Lenguaje: | EN |
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Dove Medical Press
2015
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| Acceso en línea: | https://doaj.org/article/61f5e9bf592a440fb67cf8a9514dfddc |
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| Sumario: | Mohammed A Eldesouky, Molham A Elbakary Oculoplastic Unit, Faculty of Medicine, Tanta University, Tanta, Egypt Purpose: The aim of the study was to review the demographic, clinical, and imaging features of Egyptian patients with orbital metastases.Methods: The study was a retrospective study of patients with orbital metastatic lesions over the last 15 years.Results: The study included 37 patients. Male patients represented 54.1%. The primary tumor was breast carcinoma in 21.6% of patients, with hepatocellular carcinoma (HCC) in 16.2% and cutaneous malignant melanoma in 13.5% of patients. Bronchogenic carcinoma, prostatic carcinoma, and thyroid adenocarcinoma was the primary tumor in 8.1% of cases each. The most common primary tumor in children was neuroblastoma (42.9% of pediatric patients). In 24.3% of patients, there was no history of cancer, and the orbital metastatic lesion was the first presentation of the disease. Proptosis and/or globe displacement was the presenting feature in 78.4%, followed by diplopia and limited ocular movements in 35.1%, inflammatory manifestations in 10.8%, and ptosis in 5.4%. In 54.1% the lesion involved the right orbit and in 5.4% bilateral involvement was found. Orbital imaging showed infiltrative lesion in 62.2%, mass lesion in 21.6%, isolated muscle thickening in 10.8%, and bone metastasis in 5.4%. All cases of HCC showed osteoclastic changes, and all cases of prostatic carcinoma were osteoblastic lesions.Conclusion: Orbital metastasis from HCC represented a higher incidence when compared to previous studies, probably due to the increased incidence of HCC found in the Egyptian population. Orbital metastasis can display a variety of clinical and imaging features, and a high index of suspicion is required, as 24.3% showed negative history of cancer. Keywords: orbital metastasis, orbital tumors, clinical features |
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