Clinical and imaging characteristics of orbital metastatic lesions among Egyptian patients

Mohammed A Eldesouky, Molham A Elbakary Oculoplastic Unit, Faculty of Medicine, Tanta University, Tanta, Egypt Purpose: The aim of the study was to review the demographic, clinical, and imaging features of Egyptian patients with orbital metastases.Methods: The study was a retrospective study of pa...

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Autores principales:	Eldesouky MA, Elbakary MA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/61f5e9bf592a440fb67cf8a9514dfddc
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spelling	oai:doaj.org-article:61f5e9bf592a440fb67cf8a9514dfddc2021-12-02T01:26:29ZClinical and imaging characteristics of orbital metastatic lesions among Egyptian patients1177-5483https://doaj.org/article/61f5e9bf592a440fb67cf8a9514dfddc2015-09-01T00:00:00Zhttps://www.dovepress.com/clinical-and-imaging-characteristics-of-orbital-metastatic-lesions-amo-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Mohammed A Eldesouky, Molham A Elbakary Oculoplastic Unit, Faculty of Medicine, Tanta University, Tanta, Egypt Purpose: The aim of the study was to review the demographic, clinical, and imaging features of Egyptian patients with orbital metastases.Methods: The study was a retrospective study of patients with orbital metastatic lesions over the last 15 years.Results: The study included 37 patients. Male patients represented 54.1%. The primary tumor was breast carcinoma in 21.6% of patients, with hepatocellular carcinoma (HCC) in 16.2% and cutaneous malignant melanoma in 13.5% of patients. Bronchogenic carcinoma, prostatic carcinoma, and thyroid adenocarcinoma was the primary tumor in 8.1% of cases each. The most common primary tumor in children was neuroblastoma (42.9% of pediatric patients). In 24.3% of patients, there was no history of cancer, and the orbital metastatic lesion was the first presentation of the disease. Proptosis and/or globe displacement was the presenting feature in 78.4%, followed by diplopia and limited ocular movements in 35.1%, inflammatory manifestations in 10.8%, and ptosis in 5.4%. In 54.1% the lesion involved the right orbit and in 5.4% bilateral involvement was found. Orbital imaging showed infiltrative lesion in 62.2%, mass lesion in 21.6%, isolated muscle thickening in 10.8%, and bone metastasis in 5.4%. All cases of HCC showed osteoclastic changes, and all cases of prostatic carcinoma were osteoblastic lesions.Conclusion: Orbital metastasis from HCC represented a higher incidence when compared to previous studies, probably due to the increased incidence of HCC found in the Egyptian population. Orbital metastasis can display a variety of clinical and imaging features, and a high index of suspicion is required, as 24.3% showed negative history of cancer. Keywords: orbital metastasis, orbital tumors, clinical featuresEldesouky MAElbakary MADove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 1683-1687 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Eldesouky MA Elbakary MA Clinical and imaging characteristics of orbital metastatic lesions among Egyptian patients
description	Mohammed A Eldesouky, Molham A Elbakary Oculoplastic Unit, Faculty of Medicine, Tanta University, Tanta, Egypt Purpose: The aim of the study was to review the demographic, clinical, and imaging features of Egyptian patients with orbital metastases.Methods: The study was a retrospective study of patients with orbital metastatic lesions over the last 15 years.Results: The study included 37 patients. Male patients represented 54.1%. The primary tumor was breast carcinoma in 21.6% of patients, with hepatocellular carcinoma (HCC) in 16.2% and cutaneous malignant melanoma in 13.5% of patients. Bronchogenic carcinoma, prostatic carcinoma, and thyroid adenocarcinoma was the primary tumor in 8.1% of cases each. The most common primary tumor in children was neuroblastoma (42.9% of pediatric patients). In 24.3% of patients, there was no history of cancer, and the orbital metastatic lesion was the first presentation of the disease. Proptosis and/or globe displacement was the presenting feature in 78.4%, followed by diplopia and limited ocular movements in 35.1%, inflammatory manifestations in 10.8%, and ptosis in 5.4%. In 54.1% the lesion involved the right orbit and in 5.4% bilateral involvement was found. Orbital imaging showed infiltrative lesion in 62.2%, mass lesion in 21.6%, isolated muscle thickening in 10.8%, and bone metastasis in 5.4%. All cases of HCC showed osteoclastic changes, and all cases of prostatic carcinoma were osteoblastic lesions.Conclusion: Orbital metastasis from HCC represented a higher incidence when compared to previous studies, probably due to the increased incidence of HCC found in the Egyptian population. Orbital metastasis can display a variety of clinical and imaging features, and a high index of suspicion is required, as 24.3% showed negative history of cancer. Keywords: orbital metastasis, orbital tumors, clinical features
format	article
author	Eldesouky MA Elbakary MA
author_facet	Eldesouky MA Elbakary MA
author_sort	Eldesouky MA
title	Clinical and imaging characteristics of orbital metastatic lesions among Egyptian patients
title_short	Clinical and imaging characteristics of orbital metastatic lesions among Egyptian patients
title_full	Clinical and imaging characteristics of orbital metastatic lesions among Egyptian patients
title_fullStr	Clinical and imaging characteristics of orbital metastatic lesions among Egyptian patients
title_full_unstemmed	Clinical and imaging characteristics of orbital metastatic lesions among Egyptian patients
title_sort	clinical and imaging characteristics of orbital metastatic lesions among egyptian patients
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/61f5e9bf592a440fb67cf8a9514dfddc
work_keys_str_mv	AT eldesoukyma clinicalandimagingcharacteristicsoforbitalmetastaticlesionsamongegyptianpatients AT elbakaryma clinicalandimagingcharacteristicsoforbitalmetastaticlesionsamongegyptianpatients
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Clinical and imaging characteristics of orbital metastatic lesions among Egyptian patients

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