Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression

Understanding of molecular events in cancer requires proteome-level characterisation. Here, proteome profiling of patient samples representing primary and progressed prostate cancer enables the authors to identify pathway alterations that are not reflected at the genomic and transcriptomic levels.

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Autores principales:	Leena Latonen, Ebrahim Afyounian, Antti Jylhä, Janika Nättinen, Ulla Aapola, Matti Annala, Kati K. Kivinummi, Teuvo T. L. Tammela, Roger W. Beuerman, Hannu Uusitalo, Matti Nykter, Tapio Visakorpi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/61f749925834414ebb92c52acbc5d9a6
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spelling	oai:doaj.org-article:61f749925834414ebb92c52acbc5d9a62021-12-02T14:38:50ZIntegrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression10.1038/s41467-018-03573-62041-1723https://doaj.org/article/61f749925834414ebb92c52acbc5d9a62018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03573-6https://doaj.org/toc/2041-1723Understanding of molecular events in cancer requires proteome-level characterisation. Here, proteome profiling of patient samples representing primary and progressed prostate cancer enables the authors to identify pathway alterations that are not reflected at the genomic and transcriptomic levels.Leena LatonenEbrahim AfyounianAntti JylhäJanika NättinenUlla AapolaMatti AnnalaKati K. KivinummiTeuvo T. L. TammelaRoger W. BeuermanHannu UusitaloMatti NykterTapio VisakorpiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Leena Latonen Ebrahim Afyounian Antti Jylhä Janika Nättinen Ulla Aapola Matti Annala Kati K. Kivinummi Teuvo T. L. Tammela Roger W. Beuerman Hannu Uusitalo Matti Nykter Tapio Visakorpi Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression
description	Understanding of molecular events in cancer requires proteome-level characterisation. Here, proteome profiling of patient samples representing primary and progressed prostate cancer enables the authors to identify pathway alterations that are not reflected at the genomic and transcriptomic levels.
format	article
author	Leena Latonen Ebrahim Afyounian Antti Jylhä Janika Nättinen Ulla Aapola Matti Annala Kati K. Kivinummi Teuvo T. L. Tammela Roger W. Beuerman Hannu Uusitalo Matti Nykter Tapio Visakorpi
author_facet	Leena Latonen Ebrahim Afyounian Antti Jylhä Janika Nättinen Ulla Aapola Matti Annala Kati K. Kivinummi Teuvo T. L. Tammela Roger W. Beuerman Hannu Uusitalo Matti Nykter Tapio Visakorpi
author_sort	Leena Latonen
title	Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression
title_short	Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression
title_full	Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression
title_fullStr	Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression
title_full_unstemmed	Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression
title_sort	integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/61f749925834414ebb92c52acbc5d9a6
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Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression

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