Cenerimod, a selective S1P1 receptor modulator, improves organ-specific disease outcomes in animal models of Sjögren’s syndrome

Cenerimod, a selective S1P1 receptor modulator, improves organ-specific disease outcomes in animal models of Sjögren’s syndrome

Abstract Background Sjögren’s syndrome is a systemic autoimmune disease characterized by immune cells predominantly infiltrating the exocrine glands and frequently forming ectopic lymphoid structures. These structures drive a local functional immune response culminating in autoantibody production an...

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Autores principales: Estelle Gerossier, Saba Nayar, Sylvie Froidevaux, Charlotte G. Smith, Celine Runser, Valentina Iannizzotto, Enrico Vezzali, Gabin Pierlot, Ulrich Mentzel, Mark J. Murphy, Marianne M. Martinic, Francesca Barone
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
Sjögren’s syndrome
Sphingosine-1-phosphate receptor type 1
Animal models
Immunomodulation
Cenerimod
Diseases of the musculoskeletal system
RC925-935
Acceso en línea:https://doaj.org/article/61ff86a6cb164b9daf9e959da2dde53e
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