Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus

Environmental enrichment has functional and molecular effects on mammalian hippocampus. Here, Zhang and colleagues show that environmental enrichment of mice is correlated with dorsal-ventral asymmetry in transcription and DNA methylation of the dentate gyrus.

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Autores principales:	Tie-Yuan Zhang, Christopher L. Keown, Xianglan Wen, Junhao Li, Dulcie A. Vousden, Christoph Anacker, Urvashi Bhattacharyya, Richard Ryan, Josie Diorio, Nicholas O’Toole, Jason P. Lerch, Eran A. Mukamel, Michael J. Meaney
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6205d5192507411abbaeb0e18e9e6de9
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spelling	oai:doaj.org-article:6205d5192507411abbaeb0e18e9e6de92021-12-02T17:32:15ZEnvironmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus10.1038/s41467-017-02748-x2041-1723https://doaj.org/article/6205d5192507411abbaeb0e18e9e6de92018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02748-xhttps://doaj.org/toc/2041-1723Environmental enrichment has functional and molecular effects on mammalian hippocampus. Here, Zhang and colleagues show that environmental enrichment of mice is correlated with dorsal-ventral asymmetry in transcription and DNA methylation of the dentate gyrus.Tie-Yuan ZhangChristopher L. KeownXianglan WenJunhao LiDulcie A. VousdenChristoph AnackerUrvashi BhattacharyyaRichard RyanJosie DiorioNicholas O’TooleJason P. LerchEran A. MukamelMichael J. MeaneyNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tie-Yuan Zhang Christopher L. Keown Xianglan Wen Junhao Li Dulcie A. Vousden Christoph Anacker Urvashi Bhattacharyya Richard Ryan Josie Diorio Nicholas O’Toole Jason P. Lerch Eran A. Mukamel Michael J. Meaney Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus
description	Environmental enrichment has functional and molecular effects on mammalian hippocampus. Here, Zhang and colleagues show that environmental enrichment of mice is correlated with dorsal-ventral asymmetry in transcription and DNA methylation of the dentate gyrus.
format	article
author	Tie-Yuan Zhang Christopher L. Keown Xianglan Wen Junhao Li Dulcie A. Vousden Christoph Anacker Urvashi Bhattacharyya Richard Ryan Josie Diorio Nicholas O’Toole Jason P. Lerch Eran A. Mukamel Michael J. Meaney
author_facet	Tie-Yuan Zhang Christopher L. Keown Xianglan Wen Junhao Li Dulcie A. Vousden Christoph Anacker Urvashi Bhattacharyya Richard Ryan Josie Diorio Nicholas O’Toole Jason P. Lerch Eran A. Mukamel Michael J. Meaney
author_sort	Tie-Yuan Zhang
title	Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus
title_short	Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus
title_full	Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus
title_fullStr	Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus
title_full_unstemmed	Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus
title_sort	environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/6205d5192507411abbaeb0e18e9e6de9
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Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus

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