Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses <i>In Vitro</i>

New therapeutics are urgently needed in the fight against COVID-19. Repurposing drugs that are either already approved for human use or are in advanced stages of the approval process can facilitate more rapid advances toward this goal.

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Autores principales: Nathan E. Stone, Sierra A. Jaramillo, Ashley N. Jones, Adam J. Vazquez, Madison Martz, Lora M. Versluis, Marlee O. Raniere, Haley E. Nunnally, Katherine E. Zarn, Roxanne Nottingham, Ken R. Ng, Jason W. Sahl, David M. Wagner, Steen Knudsen, Erik W. Settles, Paul Keim, Christopher T. French
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/620d821873f544a29175de77273152c9
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spelling oai:doaj.org-article:620d821873f544a29175de77273152c92021-11-03T18:15:37Z Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses <i>In Vitro</i> 2161-21292150-751110.1128/mBio.03495-20https://doaj.org/article/620d821873f544a29175de77273152c92021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03495-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 New therapeutics are urgently needed in the fight against COVID-19. Repurposing drugs that are either already approved for human use or are in advanced stages of the approval process can facilitate more rapid advances toward this goal.Nathan E. StoneSierra A. JaramilloAshley N. JonesAdam J. VazquezMadison MartzLora M. VersluisMarlee O. RaniereHaley E. NunnallyKatherine E. ZarnRoxanne NottinghamKen R. NgJason W. SahlDavid M. WagnerSteen KnudsenErik W. SettlesPaul KeimChristopher T. FrenchAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Nathan E. Stone
Sierra A. Jaramillo
Ashley N. Jones
Adam J. Vazquez
Madison Martz
Lora M. Versluis
Marlee O. Raniere
Haley E. Nunnally
Katherine E. Zarn
Roxanne Nottingham
Ken R. Ng
Jason W. Sahl
David M. Wagner
Steen Knudsen
Erik W. Settles
Paul Keim
Christopher T. French
Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses <i>In Vitro</i>
description New therapeutics are urgently needed in the fight against COVID-19. Repurposing drugs that are either already approved for human use or are in advanced stages of the approval process can facilitate more rapid advances toward this goal.
format article
author Nathan E. Stone
Sierra A. Jaramillo
Ashley N. Jones
Adam J. Vazquez
Madison Martz
Lora M. Versluis
Marlee O. Raniere
Haley E. Nunnally
Katherine E. Zarn
Roxanne Nottingham
Ken R. Ng
Jason W. Sahl
David M. Wagner
Steen Knudsen
Erik W. Settles
Paul Keim
Christopher T. French
author_facet Nathan E. Stone
Sierra A. Jaramillo
Ashley N. Jones
Adam J. Vazquez
Madison Martz
Lora M. Versluis
Marlee O. Raniere
Haley E. Nunnally
Katherine E. Zarn
Roxanne Nottingham
Ken R. Ng
Jason W. Sahl
David M. Wagner
Steen Knudsen
Erik W. Settles
Paul Keim
Christopher T. French
author_sort Nathan E. Stone
title Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses <i>In Vitro</i>
title_short Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses <i>In Vitro</i>
title_full Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses <i>In Vitro</i>
title_fullStr Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses <i>In Vitro</i>
title_full_unstemmed Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses <i>In Vitro</i>
title_sort stenoparib, an inhibitor of cellular poly(adp-ribose) polymerase, blocks replication of the sars-cov-2 and hcov-nl63 human coronaviruses <i>in vitro</i>
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/620d821873f544a29175de77273152c9
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