A monoclonal antibody against KCNK9 K+ channel extracellular domain inhibits tumour growth and metastasis

A monoclonal antibody against KCNK9 K+ channel extracellular domain inhibits tumour growth and metastasis

The potassium channel KCNK9 mediates important biological processes and is often overexpressed in breast and lung cancers. In this study, the authors developed a specific monoclonal antibody against the extracellular domain of KCNK9 and show that it inhibits cancer growth and metastasis in vivothrou...

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Autores principales: Han Sun, Liqun Luo, Bachchu Lal, Xinrong Ma, Lieping Chen, Christine L. Hann, Amy M. Fulton, Daniel J. Leahy, John Laterra, Min Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/621136ed5d044eb9bc72178de246e111
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