A monoclonal antibody against KCNK9 K+ channel extracellular domain inhibits tumour growth and metastasis

The potassium channel KCNK9 mediates important biological processes and is often overexpressed in breast and lung cancers. In this study, the authors developed a specific monoclonal antibody against the extracellular domain of KCNK9 and show that it inhibits cancer growth and metastasis in vivothrou...

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Auteurs principaux: Han Sun, Liqun Luo, Bachchu Lal, Xinrong Ma, Lieping Chen, Christine L. Hann, Amy M. Fulton, Daniel J. Leahy, John Laterra, Min Li
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/621136ed5d044eb9bc72178de246e111
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