ABHD4-dependent developmental anoikis safeguards the embryonic brain

During embryonic development, neural progenitor cells undergo numerous cell divisions. Here, the authors show that ABHD4-mediated developmental anoikis distinguishes the physiological delamination and the pathological detachment of progenitor cells with relevance to fetal alcohol-induced apoptosis.

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Autores principales:	Zsófia I. László, Zsolt Lele, Miklós Zöldi, Vivien Miczán, Fruzsina Mógor, Gabriel M. Simon, Ken Mackie, Imre Kacskovics, Benjamin F. Cravatt, István Katona
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/62189b9ad70741068eea632e23f22e26
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spelling	oai:doaj.org-article:62189b9ad70741068eea632e23f22e262021-12-02T19:09:54ZABHD4-dependent developmental anoikis safeguards the embryonic brain10.1038/s41467-020-18175-42041-1723https://doaj.org/article/62189b9ad70741068eea632e23f22e262020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18175-4https://doaj.org/toc/2041-1723During embryonic development, neural progenitor cells undergo numerous cell divisions. Here, the authors show that ABHD4-mediated developmental anoikis distinguishes the physiological delamination and the pathological detachment of progenitor cells with relevance to fetal alcohol-induced apoptosis.Zsófia I. LászlóZsolt LeleMiklós ZöldiVivien MiczánFruzsina MógorGabriel M. SimonKen MackieImre KacskovicsBenjamin F. CravattIstván KatonaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zsófia I. László Zsolt Lele Miklós Zöldi Vivien Miczán Fruzsina Mógor Gabriel M. Simon Ken Mackie Imre Kacskovics Benjamin F. Cravatt István Katona ABHD4-dependent developmental anoikis safeguards the embryonic brain
description	During embryonic development, neural progenitor cells undergo numerous cell divisions. Here, the authors show that ABHD4-mediated developmental anoikis distinguishes the physiological delamination and the pathological detachment of progenitor cells with relevance to fetal alcohol-induced apoptosis.
format	article
author	Zsófia I. László Zsolt Lele Miklós Zöldi Vivien Miczán Fruzsina Mógor Gabriel M. Simon Ken Mackie Imre Kacskovics Benjamin F. Cravatt István Katona
author_facet	Zsófia I. László Zsolt Lele Miklós Zöldi Vivien Miczán Fruzsina Mógor Gabriel M. Simon Ken Mackie Imre Kacskovics Benjamin F. Cravatt István Katona
author_sort	Zsófia I. László
title	ABHD4-dependent developmental anoikis safeguards the embryonic brain
title_short	ABHD4-dependent developmental anoikis safeguards the embryonic brain
title_full	ABHD4-dependent developmental anoikis safeguards the embryonic brain
title_fullStr	ABHD4-dependent developmental anoikis safeguards the embryonic brain
title_full_unstemmed	ABHD4-dependent developmental anoikis safeguards the embryonic brain
title_sort	abhd4-dependent developmental anoikis safeguards the embryonic brain
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/62189b9ad70741068eea632e23f22e26
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ABHD4-dependent developmental anoikis safeguards the embryonic brain

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