Mood alterations in mouse models of Spinocerebellar Ataxia type 1
Abstract Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by abnormal expansion of glutamine-encoding CAG repeats in the Ataxin-1 (ATXN1) gene. SCA1 is characterized by progressive motor deficits, cognitive decline, and mood changes including anxiety and depression, w...
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Main Authors: | Melissa Asher, Juao-Guilherme Rosa, Marija Cvetanovic |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/621e832c225f4b51b497deb29caef4aa |
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