Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity

Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity

Cytotoxic CD8+ T lymphocytes (CTL) often fail to kill tumour cells in one-to-one interactions. Here the authors show that these sublethal interactions from multiple CTL can add up over time and achieve tumour cell killing by additive cytotoxicity.

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Detalles Bibliográficos
Autores principales: Bettina Weigelin, Annemieke Th. den Boer, Esther Wagena, Kelly Broen, Harry Dolstra, Rob J. de Boer, Carl G. Figdor, Johannes Textor, Peter Friedl
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/62213730d2074330a309addcd60ee54f
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